Commensal microorganisms (the microbiota) live on all the surface barriers of our body and
are particularly abundant and diverse in the distal gut. The microbiota and its larger host …

Colorectal cancer is the second-leading cause of cancer-related deaths in the United States
and fourth-leading cause of cancer-related deaths worldwide. While cancer is largely …

Accumulating evidence indicates that dysregulation of microbiota-host interactions
associates with various diseases, including inflammatory bowel diseases (IBDs), colorectal …

The lack of multi-omics cancer datasets with extensive follow-up information hinders the
identification of accurate biomarkers of clinical outcome. In this cohort study, we performed …

Colorectal cancer (CRC) presents a considerable disease burden worldwide. The human
colon is also an anatomical location with the largest number of microbes. It is natural …

At a simplistic level, colorectal cancer arises from mutations in various proto-oncogenes and
tumor suppressor genes. Aside from genetically inherited factors, environmental, lifestyle …

Colorectal cancer is the third largest cancer in worldwide and has been proven to be closely
related to the intestinal microbiota. Many reports and clinical studies have shown that …

There is a growing appreciation for the importance of the gut microbiota as a therapeutic
target in various diseases. However, there are only a handful of known commensal strains …

Despite the promising advances in novel cancer therapy such as immune checkpoint
inhibitors (ICIs), limitations including therapeutic resistance and toxicity remain. In recent …

The food we consume feeds not only us, but also a vast and diverse community of
microbiota within our gastrointestinal tract. In a process of symbiotic co-evolution, the gut …