Background Both genetic and epigenetic alterations have been reported to act as driving
forces of tumorigenesis in colorectal cancer (CRC), but a growing body of evidence …

The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

Microbiota play critical roles in regulating colitis and colorectal cancer (CRC). However, it is
unclear how the microbiota generate protective immunity against these disease states. Here …

Abstract “The forgotten organ”, the human microbiome, comprises a community of
microorganisms that colonizes various sites of the human body. Through coevolution of …

Several studies have investigated links between the gut microbiome and colorectal cancer
(CRC), but questions remain about the replicability of biomarkers across cohorts and …

Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

Colorectal cancer (CRC) is a multifaceted disease influenced by both environmental and
genetic factors. A large body of literature has demonstrated the role of gut microbes in …

The fine line between human health and disease can be driven by the interplay between
host and microbial factors. This “metagenome” regulates cancer initiation, progression, and …

Increasing evidence suggests that the gut microbiome may modulate the efficacy of cancer
immunotherapy. In a B cell lymphoma patient cohort from five centers in Germany and the …

Collectively known as the microbiota, the commensal bacteria and other microorganisms
that colonize the epithelial surfaces of our body have been shown to produce small …