[HTML][HTML] Characterization of antimicrobial peptides toward the development of novel antibiotics

W Aoki, M Ueda - Pharmaceuticals, 2013 - mdpi.com
Antimicrobial agents have eradicated many infectious diseases and significantly improved
our living environment. However, abuse of antimicrobial agents has accelerated the …

Antimicrobial peptides: premises and promises

KVR Reddy, RD Yedery, C Aranha - International journal of antimicrobial …, 2004 - Elsevier
Antimicrobial peptides (AMPs) are an important component of the natural defences of most
living organisms against invading pathogens. These are relatively small (< 10kDa), cationic …

Antimicrobial peptides: possible anti-infective agents

JL Narayana, JY Chen - Peptides, 2015 - Elsevier
Multidrug-resistant bacterial, fungal, viral, and parasitic infections are major health threats.
The Infectious Diseases Society of America has expressed concern on the decrease of …

Antimicrobial peptides: a promising therapeutic strategy in tackling antimicrobial resistance

R Nuti, NS Goud, AP Saraswati… - Current medicinal …, 2017 - ingentaconnect.com
Background: Antimicrobial resistance (AMR) has posed a serious threat to global public
health and it requires immediate action, preferably long term. Current drug therapies have …

Antimicrobial peptides (AMPs): peptide structure and mode of action

YK Park, KS Hahm - BMB Reports, 2005 - koreascience.kr
Antimicrobial peptides (AMPs) have been isolated and characterized from tissues and
organisms representing virtually every kingdom and phylum. Their amino acid composition …

[HTML][HTML] Development and challenges of antimicrobial peptides for therapeutic applications

CH Chen, TK Lu - Antibiotics, 2020 - mdpi.com
More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have
been approved by the US Food and Drug Administration (FDA). Now commercialized, these …

Antimicrobial peptides (AMPs) as drug candidates: a patent review (2003–2015)

P Kosikowska, A Lesner - Expert opinion on therapeutic patents, 2016 - Taylor & Francis
ABSTRACT Introduction: Antimicrobial peptides (AMPs) represent the large group of
endogenous compounds widely distributed in nature. Due to their broad spectrum of …

Designing and optimizing new antimicrobial peptides: all targets are not the same

A Barreto-Santamaría, ME Patarroyo… - Critical Reviews in …, 2019 - Taylor & Francis
Because the resistance of microorganisms to the available antibiotics is a growing
healthcare problem worldwide, the search for new antimicrobial peptides (AMPs) that …

Mammalian antimicrobial peptides: promising therapeutic targets against infection and chronic inflammation

P Dutta, S Das - Current topics in medicinal chemistry, 2016 - ingentaconnect.com
Antimicrobial peptides (AMPs) are integral components of the host innate immune system
and functional throughout the plant and animal kingdoms. AMPs are short cationic …

[HTML][HTML] The road from host-defense peptides to a new generation of antimicrobial drugs

A Boto, JM Pérez de la Lastra, CC González - Molecules, 2018 - mdpi.com
Host-defense peptides, also called antimicrobial peptides (AMPs), whose protective action
has been used by animals for millions of years, fulfill many requirements of the …