Background: The current understanding of the pathogenesis of periodontal disease has
resulted in adjunctive use of various pharmacologic agents in periodontal therapy. The …

Background: Periodontitis is an inflammatory disease that results in bone resorption creating
bony defects, which may cause tooth loss. Various drugs have been studied using local …

Background. Statins are the recently evolved agents that aid in periodontal regeneration and
ultimately in attaining periodontal health. Atorvastatin (ATV) and Simvastatin (SMV) are …

Simvastatin (SMV) are specific competitive inhibitors which are widely used to lower
cholesterol for the treatment of hyperlipidemia and arteriosclerosis. They have shown to …

Background: Chronic periodontitis (CP) is an inflammatory condition affecting tooth‐
supporting tissues and alveolar bone that surround the tooth, leading to formation of a …

Aim Statins are known to have a beneficial effect in the treatment of chronic periodontitis
(CP). The current study was designed to investigate the effectiveness of a 1.2% atorvastatin …

Background Statins are lipid-lowering medications that work by blocking rate-limiting
enzyme in cholesterol formation. In patients with Chronic periodontitis (CP) and Diabetes …

Simvastatin (SMV) is a specific competitive inhibitor of 3-hydroxy-2-methylglutaryl coenzyme
A reductase that promotes bone formation. The present clinical trial was designed to …

Background: Simvastatin (SMV), a new locally delivered drug of class statins, is a specific
competitive inhibitor of 3-hydroxy-2-methyl-glutaryl coenzyme A reductase. Statins, besides …

Background: Etiological factors for periodontal diseases are multifactorial and one of these
etiologic agents is bacteria. Mechanical therapy itself may not eliminate the anaerobic …