[HTML][HTML] Exploring the impact of obesity on skeletal muscle function in older age
Sarcopenia is of important clinical relevance for loss of independence in older adults. The
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …
Does the amount of fat mass predict age-related loss of lean mass, muscle strength, and muscle quality in older adults?
A Koster, J Ding, S Stenholm, P Caserotti… - … Series A: Biomedical …, 2011 - academic.oup.com
Background. An excessive amount of adipose tissue may contribute to sarcopenia and may
be one mechanism underlying accelerated loss of muscle mass and strength with aging. We …
be one mechanism underlying accelerated loss of muscle mass and strength with aging. We …
Lower physical activity is associated with higher intermuscular adipose tissue in people with type 2 diabetes and peripheral neuropathy
Background Increased lipid accumulation in skeletal muscle has been linked to insulin
resistance, impaired muscle performance, and impaired physical function. It is unclear …
resistance, impaired muscle performance, and impaired physical function. It is unclear …
Intermuscular adipose tissue-free skeletal muscle mass: estimation by dual-energy X-ray absorptiometry in adults
J Kim, S Heshka, D Gallagher… - Journal of applied …, 2004 - journals.physiology.org
Skeletal muscle (SM) is a large and physiologically important compartment. Adipose tissue
is found interspersed between and within SM groups and is referred to as intermuscular …
is found interspersed between and within SM groups and is referred to as intermuscular …
Fatty infiltration of skeletal muscle: mechanisms and comparisons with bone marrow adiposity
MW Hamrick, ME McGee-Lawrence… - Frontiers in …, 2016 - frontiersin.org
Skeletal muscle and bone share common embryological origins from mesodermal cell
populations and also display common growth trajectories early in life. Moreover, muscle and …
populations and also display common growth trajectories early in life. Moreover, muscle and …
The relationships between sarcopenic skeletal muscle loss during ageing and macronutrient metabolism, obesity and onset of diabetes
AA Welch, RPG Hayhoe, D Cameron - Proceedings of the Nutrition …, 2020 - cambridge.org
Skeletal muscle is integral to the metabolism and utilisation of macronutrients; however,
substantial muscle loss and morphological changes occur with ageing. These are …
substantial muscle loss and morphological changes occur with ageing. These are …
Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …
Adipose–Muscle crosstalk in age-related metabolic disorders: The emerging roles of adipo-myokines
P Fang, Y She, M Yu, W Min, W Shang… - Ageing Research Reviews, 2023 - Elsevier
Obesity and type 2 diabetes account for a considerable proportion of the global burden of
age-related metabolic diseases. In age-related metabolic diseases, tissue crosstalk and …
age-related metabolic diseases. In age-related metabolic diseases, tissue crosstalk and …
Interplay of skeletal muscle and adipose tissue: sarcopenic obesity
Sarcopenic obesity is becoming a global health concern, owing to the rising older
population, causing cardiometabolic morbidity and mortality. Loss of muscle exceeding …
population, causing cardiometabolic morbidity and mortality. Loss of muscle exceeding …
[HTML][HTML] Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus
BH Goodpaster, FL Thaete, DE Kelley - The American journal of clinical …, 2000 - Elsevier
Background: Adipose tissue (AT) content of the thigh is generally not considered to be
associated with insulin resistance (IR), but it is unclear whether the distribution of AT in the …
associated with insulin resistance (IR), but it is unclear whether the distribution of AT in the …