Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review

C Li, K Yu, N Shyh‐Chang, Z Jiang… - Journal of cachexia …, 2022 - Wiley Online Library
Age‐associated obesity and muscle atrophy (sarcopenia) are intimately connected and are
reciprocally regulated by adipose tissue and skeletal muscle dysfunction. During ageing …

Early body composition, but not body mass, is associated with future accelerated decline in muscle quality

E Fabbri, N Chiles Shaffer… - Journal of cachexia …, 2017 - Wiley Online Library
Background Muscle quality (MQ) or strength‐to‐mass ratio declines with aging, but the rate
of MQ change with aging is highly heterogeneous across individuals. The identification of …

Understanding age-related changes in skeletal muscle metabolism: differences between females and males

BJF Gheller, ES Riddle, MR Lem… - Annual review of …, 2016 - annualreviews.org
Skeletal muscle is the largest metabolic organ system in the human body. As such,
metabolic dysfunction occurring in skeletal muscle impacts whole-body nutrient …

Adiposity, muscle mass, and muscle strength in relation to functional decline in older persons

LA Schaap, A Koster, M Visser - Epidemiologic reviews, 2013 - academic.oup.com
Aging is associated with changes in body composition and muscle strength. This review
aimed to determine the relation between different body composition measures and muscle …

Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial

BH Goodpaster, P Chomentowski… - Journal of applied …, 2008 - journals.physiology.org
Considerable evidence suggests that the loss of strength and muscle mass appear to be
inevitable consequences of aging. Moreover, aging is associated with an increase in body …

Metabolic syndrome and its associations with components of sarcopenia in overweight and obese older adults

J Mesinovic, LB McMillan, C Shore-Lorenti… - Journal of clinical …, 2019 - mdpi.com
Ageing, obesity and the metabolic syndrome (MetS) may all contribute to poor muscle health
(sarcopenia). This study aimed to determine the cross-sectional associations between MetS …

[HTML][HTML] Interrelations between fat distribution, muscle lipid content, adipocytokines, and insulin resistance: effect of moderate weight loss in older women

G Mazzali, V Di Francesco, E Zoico, F Fantin… - The American journal of …, 2006 - Elsevier
Background: Interrelations between fat distribution, muscle lipid infiltration, adipocytokines,
insulin resistance, and moderate weight loss have not been investigated in obese older …

Muscle‐to‐fat ratio identifies functional impairments and cardiometabolic risk and predicts outcomes: biomarkers of sarcopenic obesity

PC Yu, CC Hsu, WJ Lee, CK Liang… - Journal of cachexia …, 2022 - Wiley Online Library
Background Sarcopenic obesity aims to capture the risk of functional decline and
cardiometabolic diseases, but its operational definition and associated clinical outcomes …

Association between insulin resistance and low relative appendicular skeletal muscle mass: evidence from a cohort study in community-dwelling older men and …

H Alemán-Mateo, MT López Teros… - … Series A: Biomedical …, 2014 - academic.oup.com
Background. It has been hypothesized that insulin resistance plays a role in the
development of the loss of skeletal muscle; however, no cohort studies on insulin resistance …