Vitamin C inhibits lipid deposition through GSK-3β/mTOR signaling in the liver of zebrafish
D Liu, Y Gu, Q Pang, Q Han, A Li, W Wu… - Fish physiology and …, 2020 - Springer
In this study, the mechanism that VC inhibits lipid deposition through GSK-3β/mTOR
signaling was investigated in the liver of Danio rerio. The results indicated that 0.5-and 1.0 …
signaling was investigated in the liver of Danio rerio. The results indicated that 0.5-and 1.0 …
Effects of simvastatin on the PXR signaling pathway and the liver histology in Mugilogobius abei
C Wang, P Ku, X Nie, S Bao, Z Wang, K Li - Science of The Total …, 2019 - Elsevier
Simvastatin is one of the most commonly cholesterol-lowering prescribed drugs all over the
world. With the increase of consumption of these pharmaceuticals and subsequent their …
world. With the increase of consumption of these pharmaceuticals and subsequent their …
SREBP-1 and LXRα pathways mediated Cu-induced hepatic lipid metabolism in zebrafish Danio rerio
YX Pan, MQ Zhuo, DD Li, YH Xu, K Wu, Z Luo - Chemosphere, 2019 - Elsevier
The present study was performed to explore the underlying molecular mechanism of Cu-
induced disorder of lipid metabolism in fish. To this end, adult zebrafish were exposed to …
induced disorder of lipid metabolism in fish. To this end, adult zebrafish were exposed to …
Astaxanthin, bile acid and chlorogenic acid attenuated the negative effects of high-fat diet on the growth, lipid deposition, and liver health of Oncorhynchus mykiss
W Zhao, R Yao, HL Wei, YC Guo, AQ Chen, BY Chen - Aquaculture, 2023 - Elsevier
This study aimed to examine the effects of high-fat diets supplemented with astaxanthin,
chlorogenic acid, and bile acid on the growth, lipid accumulation, oxidation resistance …
chlorogenic acid, and bile acid on the growth, lipid accumulation, oxidation resistance …
Differential modulation of cellular antioxidant status in zebrafish liver and kidney exposed to low dose arsenic trioxide
S Sarkar, S Mukherjee, A Chattopadhyay… - Ecotoxicology and …, 2017 - Elsevier
Zebrafish were exposed to a nonlethal dose (1/350LC 50; 50 µg/L) of As 2 O 3 and sampled
at 7, 15, 30, 60 and 90 days of treatment. The oxidative stress response was assessed in …
at 7, 15, 30, 60 and 90 days of treatment. The oxidative stress response was assessed in …
Simvastatin as an emerging pollutant on non-target aquatic invertebrates: effects on antioxidant-related genes in Daphnia magna
S Liu, J Lin, R Ding, X Nie - Environmental Science and Pollution …, 2022 - Springer
Simvastatin (SIM) is one of the most widely used lipid-lowering drugs and consequently has
been frequently detected in various waters. However, its potential adverse effects and toxic …
been frequently detected in various waters. However, its potential adverse effects and toxic …
Simvastatin affects the PPARα signaling pathway and causes oxidative stress and embryonic development interference in Mugilogobius abei
C Wang, T Tang, Y Wang, X Nie, K Li - Aquatic Toxicology, 2021 - Elsevier
Simvastatin (SV) is a common hypolipidemic drug in clinical medicine that can reduce
endogenous cholesterol biosynthesis by inhibiting hydroxyl-methyl-glutaryl coenzyme A …
endogenous cholesterol biosynthesis by inhibiting hydroxyl-methyl-glutaryl coenzyme A …
[HTML][HTML] Iprodione induces hepatotoxicity in zebrafish by mediating ROS generation and upregulating p53 signalling pathway
W Hu, G Chen, W Yuan, C Guo, F Liu, S Zhang… - Ecotoxicology and …, 2024 - Elsevier
Iprodione is an effective and broad-spectrum fungicide commonly used for early disease
control in fruit trees and vegetables. Due to rainfall, iprodione often finds its way into water …
control in fruit trees and vegetables. Due to rainfall, iprodione often finds its way into water …
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio)
G Ran, L Ying, L Li, Q Yan, W Yi, C Ying, H Wu, X Ye - PLoS One, 2017 - journals.plos.org
Defective lipid metabolism is associated with increased risk of various chronic diseases,
such as obesity, cardiovascular diseases, and diabetes. Resveratrol (RSV), a natural …
such as obesity, cardiovascular diseases, and diabetes. Resveratrol (RSV), a natural …
Genistein protects benzotriazole ultraviolet stabilizer UV-234-induced hepatotoxicity by modulating ROS/Nrf2 and NF-κB signaling in yellow catfish (Pelteobagrus …
S Li, J Xie, X Li, Q Li, X Tang, D Yu, X Xiong - … Biochemistry and Physiology …, 2023 - Elsevier
Benzotriazole ultraviolet stabilizers (BUVSs) are a group of anthropogenic chemicals widely
used in commodities and industrial products, posing a potential threat to aquatic organisms …
used in commodities and industrial products, posing a potential threat to aquatic organisms …