It is well documented that diarrhetic shellfish poisoning (DSP) toxins have strong genetic
toxicity, cytotoxicity and oxidative damage to bivalve species. However, these toxic effects …

Indoxyl sulfate (IS) is a metabolic byproduct of indole metabolism. IS readily interacts with
the mitochondrial redox metabolism, leading to altered renal function. The β-carotene …

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease with a broad
spectrum of liver injury. Oxidant stress is believed to be the pathogenesis of NAFLD as the …

In this study, treatment of C57BL/6J (wild type, WT) mice fed a high-fat diet (HFD) with
retinoic acid (RA) decreased body weight and subcutaneous and visceral fat content …

This study aimed to investigate the changes in the composition of Pueraria lobata after
fermentation by Pichia kudriavzevii and its impact on the antioxidant capacity of zebrafish …

Abstract Analysis of the Pacific oyster Crassostrea gigas annotated genome revealed genes
with conserved sequences belonging to typical cap 'n'collar Nrf2 domain, a major player in …

Chronic kidney disease (CKD) is problem that has become one of the major issues affecting
public health. Extensive clinical data suggests that the prevalence of hyperlipidemia in CKD …

Liver insufficiency and damage are major causes of death and disease worldwide and may
result from exposure to environmental toxicants, specific combinations or dosages of …

The aim of this study was to investigate the effects of naproxen on the gene expression of
antioxidant enzymes in adult zebrafish. Surprisingly, after 2 weeks exposure no significant …

Although the hepatotoxicity of thifluzamide in zebrafish has been characterized, its toxic
mechanisms have not been fully explored. The present study demonstrated that thifluzamide …