This study sought to determine whether afferent feedback associated with peripheral muscle
fatigue inhibits central motor drive (CMD) and thereby limits endurance exercise …

Exercise-induced fatigue influences the excitability of the motor pathway during single-joint
isometric contractions. This study sought to investigate the influence of fatigue on …

We investigated the role of somatosensory feedback from locomotor muscles on central
motor drive (CMD) and the development of peripheral fatigue during high‐intensity …

Muscle fatigue is a reduction in the capacity to exert force and may involve a “central”
component originating in the brain and/or spinal cord. Here we examined whether …

Aim The voluntary termination of exercise has been hypothesized to occur at a sensory
tolerance limit, which is affected by feedback from group III and IV muscle afferents, and is …

The excitability of the motor cortex increases as fatigue develops during sustained single-
joint contractions, but there are no previous reports on how corticospinal excitability is …

We asked whether the central effects of fatiguing locomotor muscle fatigue exert an
inhibitory influence on central motor drive to regulate the total degree of peripheral fatigue …

New Findings What is the central question of this study? We asked whether exercise
performance is regulated during all‐out repeated sprints (involving peak cycling‐specific …

Key points Fatigue and muscle pain induced in a remote muscle group has been shown to
alter neuromuscular performance in exercising muscles. Inhibitory neural feedback …

Greater peripheral quadriceps fatigue at the voluntary termination of single-leg knee-
extensor exercise (KE), compared with whole-body cycling, has been attributed to confining …