Effects of MEK1/2 inhibitor U0126 on FGF10-enhanced buffalo oocyte maturation in vitro

S Du, Y Wang, F Lu, W Zhou - Reproductive Biology, 2024 - Elsevier
Abstract Fibroblast growth factor 10 (FGF10) plays critical roles in oocyte maturation and
embryonic development; however, the specific pathway by which FGF10 promotes in vitro …

Beneficial effects of fibroblast growth factor 10 supplementation during in vitro maturation of buffalo cumulus-oocyte complexes

S Du, Y Wang, X Yang, X Liu, K Deng, M Chen, X Yan… - Theriogenology, 2023 - Elsevier
Abstract Fibroblast growth factor 10 (FGF10) is an important regulator of the mammalian
cumulus-oocyte complex that plays a crucial role in oocyte maturation. In this study, we …

Effects of FGF10 on Bovine Oocyte Meiosis Progression, Apoptosis, Embryo Development and Relative Abundance of Developmentally Important Genes In Vitro

RF Pomini Pinto, PK Fontes, B Loureiro… - … in Domestic Animals, 2015 - Wiley Online Library
Contents Fibroblast growth factor (FGF10) acts at the cumulus oocyte complex, increasing
the expression of cumulus cell expansion‐related genes and oocyte competency genes. We …

GDF8 activates p38 MAPK signaling during porcine oocyte maturation in vitro

JD Yoon, SU Hwang, E Kim, M Jin, S Kim, SH Hyun - Theriogenology, 2017 - Elsevier
Abstract Growth Differentiation Factor 8 (GDF8) is a member of the transforming growth
factor-β (TGF-β) family and has been identified as a strong physiological regulator. This …

[HTML][HTML] Supplementation with fibroblast growth factor 7 during in vitro maturation of porcine cumulus-oocyte complexes improves oocyte maturation and early …

H Zheng, H Choi, D Oh, M Kim, L Cai… - Frontiers in Veterinary …, 2023 - frontiersin.org
In vitro generation of porcine embryos is an indispensable method in the realms of both
agriculture and biomedicine. Nonetheless, the extant procedures encounter substantial …

257 EFFECTS OF FIBROBLAST GROWTH FACTOR 8 ON CUMULUS EXPANSION AND NUCLEAR MATURATION IN BOVINE CUMULUS–OOCYTE COMPLEXES

CM Ormond, PF Lima, DT Jardina-Sartor… - Reproduction …, 2012 - CSIRO Publishing
Recent data indicate that fibroblast growth factor (FGF) signalling regulates oocyte
developmental competence. Fibroblast growth factor 10 enhanced nuclear maturation …

Fibroblast growth factor 10 markedly improves in vitro maturation of porcine cumulus‐oocyte complexes

YJ Son, SE Lee, H Hyun, MY Shin… - Molecular …, 2017 - Wiley Online Library
Growth factors synthesized by ovarian somatic cells affect cumulus cell expansion and
oocyte maturation in vitro. Fibroblast growth factor 10 (FGF10), for example, is a known …

Exogenous growth differentiation factor 9 in oocyte maturation media enhances subsequent embryo development and fetal viability in mice

CX Yeo, RB Gilchrist, JG Thompson… - Human …, 2008 - academic.oup.com
BACKGROUND Successful oocyte in vitro maturation (IVM) would eliminate the need for
hormonal stimulation used in assisted reproduction techniques. Unfortunately, oocytes …

[HTML][HTML] Epidermal Growth Factor-Mediated Mitogen-Activated Protein Kinase3/1 Pathway Is Conducive to In Vitro Maturation of Sheep Oocytes

H Ni, X Sheng, X Cui, M Gu, Y Liu, X Qi, S Xing… - PLoS One, 2015 - journals.plos.org
Epidermal growth factor (EGF) has been shown to facilitate the in vitro maturation of sheep
oocytes, and enhance embryo's capability for further development. However, such kind of …

Importance of the GDF9 signaling pathway on cumulus cell expansion and oocyte competency in sheep

SR Varnosfaderani, S Ostadhosseini, M Hajian… - Theriogenology, 2013 - Elsevier
Acquisition of developmental competency in cumulus oocyte complexes (COCs) is derived
from endocrine hormones and oocyte secreted factors. The contribution of these factors in …