Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

Oxidant mechanisms in response to ambient air particles

B González-Flecha - Molecular aspects of medicine, 2004 - Elsevier
The toxic effects of air pollution are widely documented. In recent years, however, there has
been an increasing interest in the study of the health effects of particulate matter (PM), a …

Oxidative stress and air pollution exposure

M Lodovici, E Bigagli - Journal of toxicology, 2011 - Wiley Online Library
Air pollution is associated with increased cardiovascular and pulmonary morbidity and
mortality. The mechanisms of air pollution‐induced health effects involve oxidative stress …

The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses

K Sawyer, S Mundandhara, AJ Ghio… - Journal of Toxicology …, 2009 - Taylor & Francis
Epidemiologic and occupational studies demonstrated that ambient particulate matter (PM)
and diesel exhaust particles (DEP) exert deleterious effects on human cardiopulmonary …

Stimulation of human and rat alveolar macrophages by urban air particulates: effects on oxidant radical generation and cytokine production

S Becker, JM Soukup, MI Gilmour, RB Devlin - Toxicology and applied …, 1996 - Elsevier
A number of epidemiological studies have associated increased cardiopulmonary mortality
and hospital admissions with episodes of high particulate air pollution. Inhaled particles …

[PDF][PDF] The role of reactive oxygen species and oxidative stress in mediating particulate matter injury

T Xia, M Kovochich, A Nel - Clin Occup Environ Med, 2006 - academia.edu
Several plausible mechanisms have been proposed to explain the adverse health effects of
particulate matter (PM) in polluted ambient air [1]. To date, experimental support has been …

Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: further mechanistic studies

S Becker, S Mundandhara, RB Devlin… - Toxicology and applied …, 2005 - Elsevier
In order to better understand how ambient air particulate matter (PM) affect lung health, the
two main airway cell types likely to interact with inhaled particles, alveolar macrophages …

Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic …

A Valavanidis, K Fiotakis… - Journal of Environmental …, 2008 - Taylor & Francis
Air pollution has been considered a hazard to human health. In the past decades, many
studies highlighted the role of ambient airborne particulate matter (PM) as an important …

Contribution of lung macrophages to the inflammatory responses induced by exposure to air pollutants

K Hiraiwa, SF van Eeden - Mediators of inflammation, 2013 - Wiley Online Library
Large population cohort studies have indicated an association between exposure to
particulate matter and cardiopulmonary morbidity and mortality. The inhalation of toxic …

Pathogenic role of air pollution particulate matter in cardiometabolic disease: evidence from mice and humans

T Marchini, A Zirlik, D Wolf - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Air pollution is a considerable global threat to human health that dramatically
increases the risk for cardiovascular pathologies, such as atherosclerosis, myocardial …