Regulatory T Cells in Multiple Sclerosis Diagnostics—What Do We Know So Far?

B Arneth - Journal of Personalized Medicine, 2023 - mdpi.com
Background: Multiple sclerosis (MS) is an autoimmune disorder that affects the central
nervous system (CNS) through inflammation. MS symptoms become acute if the disease …

The proportion of peripheral regulatory T cells in patients with Multiple Sclerosis: A meta-analysis

YF Li, SX Zhang, XW Ma, YL Xue, C Gao, XY Li… - Multiple sclerosis and …, 2019 - Elsevier
Background Accumulating evidence indicates that regulatory T cells (Tregs) play an
important role in the maintenance of immune tolerance. And dysfunction or deficiency of …

The role of regulatory T cells in multiple sclerosis

AL Zozulya, H Wiendl - Nature clinical practice Neurology, 2008 - nature.com
The dysregulation of inflammatory responses and of immune self-tolerance is considered to
be a key element in the autoreactive immune response in multiple sclerosis (MS) …

Increased frequency of CD4+ CD25high CD127low/− regulatory T cells in patients with multiple sclerosis

M Khosravi, N Majdinasab, A Amari, AA Ghadiri - Gene Reports, 2019 - Elsevier
Background Multiple sclerosis (MS), one of the most common diseases of the central
nervous system (CNS), is characterized by demyelination and chronic inflammation of the …

Identification of regulatory T cell molecules associated with severity of multiple sclerosis

MA Tapia-Maltos, I Treviño-Frenk… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background: Regulatory CD4+ T cells (Tregs) exhibit functional alterations in patients with
multiple sclerosis (MS). Transforming growth factor (TGF)-β is a key regulator of Treg …

Regulatory T cells in multiple sclerosis

K Kimura - Clinical and Experimental Neuroimmunology, 2020 - Wiley Online Library
Regulatory T (Treg) cells are known to suppress excessive inflammation in autoimmune
diseases, including multiple sclerosis (MS). Accumulating evidence suggests that the …

Disturbed regulatory T cell homeostasis in multiple sclerosis

K Venken, N Hellings, R Liblau, P Stinissen - Trends in molecular medicine, 2010 - cell.com
The pathological features of multiple sclerosis (MS), a chronic inflammatory disorder of the
central nervous system, support an autoimmune etiology. Strong evidence has been …

Regulatory T cell therapy for multiple sclerosis: Breaching (blood-brain) barriers

J Verreycken, P Baeten, B Broux - Human Vaccines & …, 2022 - Taylor & Francis
Multiple sclerosis (MS) is an autoimmune disorder causing demyelination and
neurodegeneration in the central nervous system. MS is characterized by disturbed motor …

Characterization of regulatory t-cells in multiple sclerosis patients treated with interferon beta-1a

M Ebrahimimonfared, A Ganji, S Zahedi… - CNS & Neurological …, 2018 - ingentaconnect.com
Background: Regulatory T-Cells (Treg Cells), as one of the immune system components,
have been highly effective in the autoimmune diseases prevention, particularly multiple …

Regulatory T-cell as orchestra leader in immunosuppression process of multiple sclerosis

F Jadidi-Niaragh, A Mirshafiey - Immunopharmacology and …, 2011 - Taylor & Francis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous
system characterized by perivascular inflammation and demyelination and loss of …