A novel function of microRNA 130a-3p in hepatic insulin sensitivity and liver steatosis

F Xiao, J Yu, B Liu, Y Guo, K Li, J Deng, J Zhang… - Diabetes, 2014 - Am Diabetes Assoc
MicroRNAs (miRNAs) are endogenous, noncoding, short, single-stranded RNAs that are
evolutionarily conserved and believed to play a role in controlling a variety of biological …

[HTML][HTML] Saturated fatty acid-induced miR-195 impairs insulin signaling and glycogen metabolism in HepG2 cells

WM Yang, HJ Jeong, SY Park, W Lee - FEBS letters, 2014 - Elsevier
MicroRNAs (miRNAs) play an important role in insulin signaling and insulin secretion, but
the role of miRNAs in the association between obesity and hepatic insulin resistance is …

The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice

N Nakanishi, Y Nakagawa, N Tokushige, N Aoki… - Biochemical and …, 2009 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNA that post-transcriptionally regulates gene
expression. Some miRNAs have been proposed to be associated with obesity. However …

MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids

X Fu, B Dong, Y Tian, P Lefebvre… - The Journal of …, 2015 - Am Soc Clin Investig
Type 2 diabetes (T2D) is characterized by insulin resistance and increased hepatic glucose
production, yet the molecular mechanisms underlying these abnormalities are poorly …

Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice

R Liu, M Wang, E Li, Y Yang, J Li, S Chen… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Obesity is associated with an increased risk of developing insulin resistance (IR) and type 2
diabetes (T2D). A diverse group of factors including miRNA has been implicated in the …

Hepatic miR‐125b inhibits insulin signaling pathway by targeting PIK3CD

X Du, X Li, L Chen, M Zhang, L Lei… - Journal of cellular …, 2018 - Wiley Online Library
Insulin resistance is often characterized as the most critical factor contributing to the
development of (T2D) type 2 diabetes. MicroRNAs (miRNAs) are endogenous non‐coding …

Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

YH Hung, M Kanke, CL Kurtz, R Cubitt… - Physiological …, 2019 - journals.physiology.org
MicroRNAs (miRNAs) are important posttranscriptional regulators of metabolism and energy
homeostasis. Dysregulation of certain miRNAs in the liver has been shown to contribute to …

Down-regulation of MicroRNA-592 in obesity contributes to hyperglycemia and insulin resistance

Y Song, L Wu, M Li, X Xiong, Z Fang, J Zhou, G Yan… - …, 2019 - thelancet.com
Background Many studies have demonstrated that microRNAs, a class of small and non-
coding RNA molecules, play an important role in the regulation of glucose and lipid …

[HTML][HTML] MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease

XC Wang, XR Zhan, XY Li, JJ Yu… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To assess the regulatory effect of microRNA-185 (miR-185) on lipid metabolism and the
insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model …

Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes

A He, L Zhu, N Gupta, Y Chang… - Molecular endocrinology, 2007 - academic.oup.com
Micro-RNAs (miRNAs) have been suggested to play pivotal roles in multifarious diseases
associated with the posttranscriptional regulation of protein-coding genes. In this study, we …