Photo-Dynamic Therapy: Cavitary Photo-Illumination of Malignant Cerebral Tumours Using a Laser Coupled Inflatable Balloon

PJ Muller, BC Wilson - Canadian Journal of Neurological Sciences, 1985 - cambridge.org
Interest in photodynamic therapy of malignant brain tumours has been growing in recent
years as intra-operative laser applications become more available. We have developed an …

Photodynamic therapy of C6-implanted glioma cells in the rat brain employing second-generation photosensitizer talaporfin sodium

H Namatame, J Akimoto, H Matsumura… - Photodiagnosis and …, 2008 - Elsevier
OBJECT: The usefulness of photodynamic therapy (PDT) as a local therapy for malignant
glioma was evaluated by investigating histological changes in a rat C6 glioma model treated …

Preclinical evaluation of benzoporphyrin derivative combined with a light-emitting diode array for photodynamic therapy of brain tumors

MH Schmidt, KW Reichert II, K Ozker, GA Meyer… - Pediatric …, 1999 - karger.com
Objective: The aim of this study was to investigate the second-generation photosensitizer
benzoporphyrin derivative (BPD) and a novel light source applicator based on light-emitting …

Photodynamic therapy for intracranial neoplasms: development of an image-based computer-assisted protocol for photodynamic therapy of intracranial neoplasms

TC Origitano, OH Reichman - Neurosurgery, 1993 - journals.lww.com
Abstract PHOTODYNAMIC THERAPY IS being studied as an adjuvant therapy for malignant
gliomas. Therapeutic efficacy is based on photosensitizer uptake kinetics and the ability to …

Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors

Y Muragaki, J Akimoto, T Maruyama, H Iseki… - Journal of …, 2013 - thejns.org
Object The objective of the present study was to perform a prospective evaluation of the
potential efficacy and safety of intraoperative photodynamic therapy (PDT) using talaporfin …

Application of photodynamic therapy to the treatment of atherosclerotic plaques

G Tang, S Hyman, JH Schneider Jr, SL Giannotta - Neurosurgery, 1993 - journals.lww.com
Abstract PHOTODYNAMIC THERAPY IS a therapeutic modality long studied for its
application to the treatment of malignant neoplasms. Recently, studies have suggested its …

Photodynamic therapy of malignant primary brain tumours: clinical effects, postoperative ICP, and light penetration of the brain

PJ Muller, BC Wilson - Photochemistry and photobiology, 1987 - Wiley Online Library
We are reporting our experience with intraoperative PDT in 32 patients with malignant
supratentorial gliomas; in 19 cases the tumour was recurrent. There were 20 males and 12 …

The Effect of Hypothermia and Hyperthermia on Photodynamic Therapy of Normal Brain: 141

MO Dereski, L Madigan, M Chopp - Neurosurgery, 1995 - journals.lww.com
Abstract THE EFFECT OF whole body hyperthermia and hypothermia in conjunction with
photodynamic therapy (PDT) was determined on normal rat brain. Hyperthermia animals …

Non-invasive Photodynamic Therapy in Brain Cancer by Use of Tb3+-Doped LaF3 Nanoparticles in Combination with Photosensitizer Through X-ray Irradiation: A …

MH Chen, YJ Jenh, SK Wu, YS Chen… - Nanoscale research …, 2017 - Springer
The use of photodynamic therapy (PDT) in the treatment of brain cancer has produced
exciting results in clinical trials over the past decade. PDT is based on the concept that a …

Sensitivity of 9L gliosarcomas to photodynamic therapy

M Chopp, MO Dereski, L Madigan… - Radiation …, 1996 - meridian.allenpress.com
Photodynamic therapy (PDT) has been used clinically for the treatment of malignant brain
gliomas. However, the efficacy of this treatment to date has remained equivocal. This study …