Preventive Effects of Schisandrin A, A Bioactive Component of Schisandra chinensis, on Dexamethasone-Induced Muscle Atrophy
MH Yeon, H Choi, HS Jun - Nutrients, 2020 - mdpi.com
Muscle wasting is caused by various factors, such as aging, cancer, diabetes, and chronic
kidney disease, and significantly decreases the quality of life. However, therapeutic …
kidney disease, and significantly decreases the quality of life. However, therapeutic …
Evaluating the protective effects and mechanisms of diallyl disulfide on interlukin‐1β‐induced oxidative stress and mitochondrial apoptotic signaling pathways in …
The protective effects and mechanisms of DADS on IL‐1β‐mediated oxidative stress and
mitochondrial apoptosis were investigated in C28I2 human chondrocytes. The effect of …
mitochondrial apoptosis were investigated in C28I2 human chondrocytes. The effect of …
Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway
RK Gara, VK Srivastava, S Duggal, JK Bagga… - Journal of biomedical …, 2015 - Springer
Background Despite the recent progress in screening and therapy, a majority of prostate
cancer cases eventually attain hormone refractory and chemo-resistant attributes …
cancer cases eventually attain hormone refractory and chemo-resistant attributes …
RKI‐1447 suppresses colorectal carcinoma cell growth via disrupting cellular bioenergetics and mitochondrial dynamics
L Li, Q Chen, Y Yu, H Chen, M Lu… - Journal of Cellular …, 2020 - Wiley Online Library
Accumulated evidence suggested the importance of the Rho/Rho‐kinase (ROCK) signaling
pathway in cancer proliferation and invasion. However, its role in colorectal carcinoma …
pathway in cancer proliferation and invasion. However, its role in colorectal carcinoma …
Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells
HJ Wang, YY Jiang, XF Wei, H Huang… - Free Radical …, 2010 - Taylor & Francis
The pharmacological activity of polyphenolic silibinin from milk thistle (Silybum marianum) is
primarily due to its antioxidant property. However, this study found that silibinin promoted …
primarily due to its antioxidant property. However, this study found that silibinin promoted …
Shenqi Fuzheng injection facilitates skeletal muscle mitophagy mediated by the ubiquitination of HIF‐1α to ameliorate cancer‐associated fatigue
W Guo, S Liu, H Xia, J Luo, H Chen… - Journal of Cellular …, 2024 - Wiley Online Library
Cancer‐related fatigue (CRF) significantly impacts the quality of life of cancer patients. This
study investigates the therapeutic potential of Shenqi Fuzheng injection (SFI) in managing …
study investigates the therapeutic potential of Shenqi Fuzheng injection (SFI) in managing …
Rutin Prevents Dexamethasone-Induced Muscle Loss in C2C12 Myotube and Mouse Model by Controlling FOXO3-Dependent Signaling
YS Hah, WK Lee, SJ Lee, SY Lee, JH Seo, EJ Kim… - Antioxidants, 2023 - mdpi.com
One of the causes of sarcopenia is that homeostasis between anabolism and catabolism
breaks down due to muscle metabolism changes. Rutin has shown antioxidant and anti …
breaks down due to muscle metabolism changes. Rutin has shown antioxidant and anti …
Higenamine combined with [6]‐gingerol suppresses doxorubicin‐triggered oxidative stress and apoptosis in cardiomyocytes via upregulation of PI3K/Akt pathway
YL Chen, XD Zhuang, ZW Xu, LH Lu… - Evidence‐Based …, 2013 - Wiley Online Library
Sini decoction is a well‐known formula of traditional Chinese medicine, which has been
used to treat cardiovascular disease for many years. Previously, we demonstrated that Sini …
used to treat cardiovascular disease for many years. Previously, we demonstrated that Sini …
Silibinin restores the sensitivity of cisplatin and taxol in A2780-resistant cell and reduces drug-induced hepatotoxicity
Z Yang, Q Pan, D Zhang, J Chen, Y Qiu… - Cancer management …, 2019 - Taylor & Francis
Purpose Ovarian cancer is the most lethal cancer among all gynaecological malignancies.
The combination theraputics of cisplatin and taxol is widely used in clinicals for ovarian …
The combination theraputics of cisplatin and taxol is widely used in clinicals for ovarian …
Selumetinib attenuates skeletal muscle wasting in murine cachexia model through ERK inhibition and AKT activation
Y Quan-Jun, H Yan, H Yong-Long, W Li-Li, L Jie… - Molecular cancer …, 2017 - AACR
Cancer cachexia is a multifactorial syndrome affecting the skeletal muscle. Previous clinical
trials showed that treatment with MEK inhibitor selumetinib resulted in skeletal muscle …
trials showed that treatment with MEK inhibitor selumetinib resulted in skeletal muscle …