The mammalian myocardium expresses four adenosine receptor (AR) subtypes: A1AR,
A2aAR, A2bAR, and A3AR. The A1AR is well known for its profound antiadrenergic effects …

The adenosine A1 receptor (A1R) inhibits β-adrenergic-induced contractile effects
(antiadrenergic action), and the adenosine A2A receptor (A2AR) both opposes the A1R …

To clarify the relative roles of A2 adenosine receptor subtypes in the regulation of coronary
flow and myocardial contractility, coronary vascular and functional responses to adenosine …

Presently, the physiological significance of myocardial adenosine A2a receptor stimulation
is unclear. In this study, the influence of adenosine A2a receptor activation on A1 receptor …

The adenosine A2A receptor (A2AR) enhances cardiac contractility, and the adenosine A1R
receptor (A1R) is antiadrenergic by reducing the adrenergic β1 receptor (β1R)-elicited …

Adenosine A2a-receptor activation enhances shortening of isolated cardiomyocytes. In the
present study the effect of A2a-receptor activation on the contractile performance of isolated …

Adenosine A2a receptors are found in coronary vascular tissue although, their presence in
myocardium is subject to investigation. Although there have been numerous studies on …

To determine whether A1 adenosine receptors (AR) participate in adenosine-induced
changes of coronary flow, isolated hearts from A1AR−/− and A1AR+/+ mice were perfused …

Adenosine, acting via A1receptors, modulates heart rate and contractility, and provides
myocardial protection during times of stress. A transgenic model of cardiac …

FOUR SUBTYPES OF ADENOSINE RECEPTORS (A1, A2A, A2B, and A3 receptors) are
known to exist (26). Traditionally, the A1-adenosine receptor has been thought to be the only …