Abstract Serotonin (5-hydroxytryptamine, 5-HT) contributes in multifarious ways to the
regulation of brain function, spanning key aspects such as the sleep-wake cycle, appetite …

The ascending serotonin (5-HT) neurons innervate the cerebral cortex, hippocampus,
septum and amygdala, all representing brain regions associated with various domains of …

The abundance of serotonin (5-HT) in the central nervous system can explain its role in the
regulation of various functions, such as sleep, feeding, sexuality, emotional status, and pain …

The abundant distribution of serotonin (5-HT) in different areas of the central nervous system
can explain the involvement of this neurotransmitter in the regulation of several functions …

The hippocampal region receives a dense serotoninergic innervation originating from both
medial and dorsal raphe nuclei. This innervation regulates hippocampal activity through the …

The serotonergic system appears to play a role in behaviors that involve a high cognitive
demand and in memory improvement or recovery from impaired cognitive performance, as …

Selective serotonin reuptake inhibitors are the mostly widely used treatment for major
depressive disorders and also are prescribed for several anxiety disorders. However, similar …

The serotonergic system is implicated in the neurobiological control of learning and memory,
both in healthy individuals and pathological disorders, although the underlying mechanisms …

The hippocampus is a major limbic target of the brainstem serotonergic neurons that
modulate fear, anxiety, and learning through postsynaptic serotonin1A receptors (5-HT1A …

Serotonin systems have been implicated in the regulation of hippocampal function.
Serotonin 5-HT2C receptors are widely expressed throughout the hippocampal formation …