When transitioning from the environment, pathogenic microorganisms must adapt rapidly to
survive in hostile host conditions. This is especially true for environmental fungi that cause …

When transitioning from the environment, pathogenic microorganisms must adapt rapidly to
survive in hostile host conditions. This is especially true for environmental fungi that cause …

When transitioning from the environment, pathogenic microorganisms must adapt rapidly to
survive in hostile host conditions. This is especially true for environmental fungi that cause …

We recently reported transposon mutagenesis as a significant driver of spontaneous
mutations in the human fungal pathogen Cryptococcus deneoformans during murine …

Climate change is predicted to increase the incidence of known fungal diseases and to
facilitate the emergence of new fungal diseases in humans and mammals. Most …

Fungi can cause devastating invasive infections, typically in immunocompromised patients.
Treatment is complicated both by the evolutionary similarity between humans and fungi and …

While increased mutation rates typically have negative consequences in multicellular
organisms, hypermutation can be advantageous for microbes adapting to the environment …

Increasing temperatures associated with climate change have the potential for far-reaching
impact on human health and disease vectors, including fungal pathogens. Pathogenic fungi …

Cryptococcus neoformans infections cause approximately 15% of AIDS-related deaths
owing to a combination of limited antifungal therapies and drug resistance. A collection of …

Microorganisms survive and compete within their environmental niches and avoid
evolutionary stagnation by stochastically acquiring mutations that enhance fitness. Although …