Monitoring of dabigatran therapy using Hemoclot® Thrombin Inhibitor assay in patients with atrial fibrillation
M Samoš, L Stančiaková, J Ivanková, J Staško… - Journal of thrombosis …, 2015 - Springer
Dabigatran, a new direct thrombin inhibitor, achieves strong anticoagulation that is more
predictable than warfarin. Nevertheless, a patient on dabigatran therapy (DT) may suffer …
predictable than warfarin. Nevertheless, a patient on dabigatran therapy (DT) may suffer …
Real‐world variability in dabigatran levels in patients with atrial fibrillation
Background In clinical practice, physicians are given the choice of selecting one of two
dabigatran doses based on patient characteristics, with the lower dose typically used in …
dabigatran doses based on patient characteristics, with the lower dose typically used in …
[HTML][HTML] Relationship between plasma dabigatran concentration and activated partial thromboplastin time in Japanese patients with non-valvular atrial fibrillation
D Shimomura, Y Nakagawa, H Kondo, T Tamura… - Journal of …, 2015 - Elsevier
Background Activated partial thromboplastin time (aPTT) is recommended for monitoring
anticoagulant activity in dabigatran-treated patients; however, there are limited data in …
anticoagulant activity in dabigatran-treated patients; however, there are limited data in …
Monitoring of low dabigatran concentrations: diagnostic performance at clinically relevant decision thresholds
The direct oral anticoagulant dabigatran does not require therapeutic drug monitoring,
however emergency measurements are gaining importance. Current assays feature good …
however emergency measurements are gaining importance. Current assays feature good …
A systematic review and meta‐analysis of dabigatran peak and trough concentration in adults
JW Ng, NA Mohd Tahir, PKL Chin… - British Journal of …, 2022 - Wiley Online Library
Dabigatran etexilate is an oral direct thrombin inhibitor used in preventing thromboembolism
in patients with atrial fibrillation and several other conditions. Routine dabigatran …
in patients with atrial fibrillation and several other conditions. Routine dabigatran …
On the monitoring of dabigatran treatment in “real life” patients with atrial fibrillation
M Skeppholm, P Hjemdahl, JP Antovic, J Muhrbeck… - Thrombosis research, 2014 - Elsevier
Introduction The oral direct thrombin inhibitor dabigatran is increasingly used to prevent
thromboembolic stroke in patients with atrial fibrillation (AF). Routine laboratory monitoring is …
thromboembolic stroke in patients with atrial fibrillation (AF). Routine laboratory monitoring is …
A proposal for dose‐adjustment of dabigatran etexilate in atrial fibrillation guided by thrombin time
PKL Chin, DFB Wright, DM Patterson… - British journal of …, 2014 - Wiley Online Library
Dabigatran is an oral anticoagulant that is increasingly used for atrial fibrillation (AF).
Presently, many authorities state that routine laboratory coagulation monitoring is not …
Presently, many authorities state that routine laboratory coagulation monitoring is not …
The assessment of anticoagulant activity to predict bleeding outcome in atrial fibrillation patients receiving dabigatran etexilate
YT Chang, YF Hu, JN Liao, CM Chern… - Blood Coagulation & …, 2016 - journals.lww.com
Special circumstances may require the measurement of the anticoagulant effect of
dabigatran etexilate. No data currently link any given coagulation test to bleeding outcomes …
dabigatran etexilate. No data currently link any given coagulation test to bleeding outcomes …
[HTML][HTML] Frequency and predictors of bleeding complications associated with anti-coagulant therapy using dabigatran in Japanese patients with atrial fibrillation
H Katoh, T Nozue, T Asada, K Nakashima… - American Journal of …, 2014 - ncbi.nlm.nih.gov
Background: Few data exist regarding frequency and predictors of bleeding complications
associated with anticoagulant therapy using dabigatran in Japanese patients with atrial …
associated with anticoagulant therapy using dabigatran in Japanese patients with atrial …
[HTML][HTML] Global Thrombosis Test–a possible monitoring system for the effects and safety of dabigatran
K Otsui, DA Gorog, J Yamamoto, T Yoshioka, S Iwata… - Thrombosis …, 2015 - Springer
Background Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of
stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran …
stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran …