Randomised controlled trial of inhaled corticosteroids in patients with chronic obstructive pulmonary disease

J Bourbeau, MY Rouleau, S Boucher - Thorax, 1998 - thorax.bmj.com
BACKGROUND Inhaled corticosteroids are known to be beneficial for patients with asthma,
but their role in treating patients with stable chronic obstructive pulmonary disease (COPD) …

A re-evaluation of the role of inhaled corticosteroids in the management of patients with chronic obstructive pulmonary disease

A D'Urzo, JF Donohue, P Kardos… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Inhaled corticosteroids (ICS)(in fixed combinations with long-acting β2-agonists
[LABAs]) are frequently prescribed for patients with chronic obstructive pulmonary disease …

Inhaled and systemic corticosteroids in chronic obstructive pulmonary disease

JA Falk, OA Minai, Z Mosenifar - Proceedings of the American …, 2008 - atsjournals.org
Systemic and local inflammation is central to the pathophysiology of chronic obstructive
pulmonary disease (COPD). Increased levels of inflammation have been linked to a more …

Rational use of inhaled corticosteroids for the treatment of COPD

JK Quint, A Ariel, PJ Barnes - npj Primary Care Respiratory Medicine, 2023 - nature.com
Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …

Applying the wisdom of stepping down inhaled corticosteroids in patients with COPD: a proposed algorithm for clinical practice

AG Kaplan - … Journal of Chronic Obstructive Pulmonary Disease, 2015 - Taylor & Francis
Current guidelines for the management of chronic obstructive pulmonary disease (COPD)
recommend limiting the use of inhaled corticosteroids (ICS) to patients with more severe …

Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis

MB Drummond, EC Dasenbrook, MW Pitz, DJ Murphy… - Jama, 2008 - jamanetwork.com
Context Recent studies of inhaled corticosteroid (ICS) therapy for managing stable chronic
obstructive pulmonary disease (COPD) have yielded conflicting results regarding survival …

Safety of inhaled corticosteroids for treating chronic obstructive pulmonary disease

MG Matera, V Cardaci, M Cazzola… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: The frequent use of inhaled corticosteroids (ICSs), especially at higher doses,
has been accompanied by concern about both systemic and local side effects. Patients …

Risk of pneumonia with inhaled corticosteroid versus long-acting bronchodilator regimens in chronic obstructive pulmonary disease: a new-user cohort study

RL DiSantostefano, T Sampson, HV Le, D Hinds… - PLoS …, 2014 - journals.plos.org
Introduction Observational studies using case-control designs have showed an increased
risk of pneumonia associated with inhaled corticosteroid (ICS)-containing medications in …

Inhaled corticosteroids as combination therapy with β-adrenergic agonists in airways disease: present and future

KF Chung, G Caramori, IM Adcock - European journal of clinical …, 2009 - Springer
Inhaled corticosteroid (ICS) therapy in combination with long-acting β-adrenergic agonists
represents the most important treatment for chronic airways diseases such as asthma and …

Discontinuation of inhaled corticosteroids in COPD and the risk reduction of pneumonia

S Suissa, J Coulombe, P Ernst - Chest, 2015 - Elsevier
Background The widespread use of inhaled corticosteroids (ICSs) for COPD treatment has
been questioned. Recent studies of weaning some patients with COPD off ICSs found little …