Role of IL-23 and Th17 cells in airway inflammation in asthma

N Hiroshi, H Koichi - Immune Network, 2010 - oldkmbase.medric.or.kr
Asthma is characterized by chronic airway inflammation with intense eosinophil and
lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness …

[HTML][HTML] Rhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33

J Calvén, H Akbarshahi, M Menzel, CK Ayata… - Journal of translational …, 2015 - Springer
Background Bronchial smooth muscle cells (BSMCs) from severe asthmatics have been
shown to overexpress the Th2-driving and asthma-associated cytokine IL-33. However, little …

Potentiation of IL-19 expression in airway epithelia by IL-17A and IL-4/IL-13: important implications in asthma

F Huang, S Wachi, P Thai, A Loukoianov… - Journal of Allergy and …, 2008 - Elsevier
BACKGROUND: IL-17A and IL-19 are highly expressed in chronic inflammatory diseases,
such as psoriasis and asthma. IL-19 plays a significant role in the enhancement of TH2 …

[HTML][HTML] Role of IL-25 on eosinophils in the initiation of Th2 responses in allergic asthma

B Peng, L Sun, M Zhang, H Yan, G Shi, Z Xia… - Frontiers in …, 2022 - frontiersin.org
Background Eosinophils act as a secondary antigen-presenting cell (APC) to stimulate Th
cell responses against antigens. IL-25 plays a significant role in eosinophil activation in …

Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis

Y Chang, L Al-Alwan, S Audusseau… - … of Physiology-Lung …, 2014 - journals.physiology.org
Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder marked by
relative resistance to steroids. Inflammation and apoptosis have been suggested to be …

[引用][C] IL-33 and Airway Inflammation

O Keisuke, S Nakae, K Matsumoto, H Saito - Allergy Asthma Immunol Res, 2011

IL-17RA signaling in airway inflammation and bronchial hyperreactivity in allergic asthma

CR Willis, L Siegel, A Leith, D Mohn… - American journal of …, 2015 - atsjournals.org
Asthma is a heterogeneous disease characterized by airway inflammation and
hyperreactivity. IL-17 receptor A (IL-17RA) is a shared receptor subunit required for activity …

[HTML][HTML] Role of IL-23 and Th17 cells in airway inflammation in asthma

H Nakajima, K Hirose - Immune network, 2010 - ncbi.nlm.nih.gov
Asthma is characterized by chronic airway inflammation with intense eosinophil and
lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness …

IL-33 and thymic stromal lymphopoietin mediate immune pathology in response to chronic airborne allergen exposure

K Iijima, T Kobayashi, K Hara, GM Kephart… - The Journal of …, 2014 - journals.aai.org
Humans are frequently exposed to various airborne allergens in the atmospheric
environment. These allergens may trigger a complex network of immune responses in the …

Respiratory syncytial virus upregulates IL-33 expression in mouse model of virus-induced inflammation exacerbation in OVA-sensitized mice and in asthmatic subjects

A Nikonova, I Shilovskiy, M Galitskaya, A Sokolova… - Cytokine, 2021 - Elsevier
Background Bronchial asthma (BA) is a chronic disease of the airways. The great majority of
BA exacerbations are associated with respiratory viral infections. Recent findings point out a …