Aquaporins (AQP) are a family of membrane channels primarily responsible for conducting
water across cellular membranes. The availability of a large body of high resolution …

A double lipid bilayer structure containing opposing tetramers of AQP0 aquaporin, in contact
through extracellular face loop regions, was recently modeled using an intermediate …

Evolution turned aquaporins (AQPs) into the most efficient facilitators of passive water flow
through cell membranes at no expense of solute discrimination. In spite of a plethora of …

Aquaporins (AQPs) function as tetrameric structures in which each monomer has its own
permeable pathway. The combination of structural biology, molecular dynamics simulations …

1. Introduction 3621.1 The elusive water pores 3621.2 CHIP28 3622. Studies on AQP-1
3632.1 Expression of AQP1 cDNA in Xenopus oocytes 3632.2 Reconstitution of purified …

Molecular-dynamics simulations were performed on the structures of the water channel
aquaporin-1. The results provide an atomistic description of the interactions involved in the …

Despite sharing overall sequence and structural similarities, water channel aquaporin 0
(AQP0) transports water more slowly than other aquaporins. Using molecular dynamics …

Aquaporins (AQPs) are multifunctional transmembrane channel proteins permeable to water
and an expanding array of solutes. AQP-mediated ion channel activity was first observed …

Aquaporins (AQPs) are a family of integral membrane proteins, which facilitate the rapid and
yet highly selective flux of water and other small solutes across biological membranes …

Aquaporins are a family of water and small molecule channels found in organisms ranging
from bacteria to animals. One of these channels, the E. coli protein aquaporin Z (AqpZ), has …