Methods Twelve 6-9-months-old New Zealand white rabbits were used, with procedures
being conducted under the approved Institutional Animal Care and Use Committee (IACUC) …

BACKGROUND The majority of literature on bacterial flora in the disc stands disadvantaged
in utilizing traditional culture methods and targeting a single bacterium, Cutibacterium …

Recently, the role of infection of the intervertebral disc (IVD) with Cutibacterium acnes (C.
acnes) as a contributor to disc-related low back pain (LBP) has been discussed. The aim of …

In the last decade, several studies have demonstrated Cutibacterium acnes colonization in
intervertebral discs (IVDs) in patients with lumbar disc degeneration (LDD) and low back …

Introduction Multiple reports of bacterial isolates in human disc tissue have suggested a role
of low-grade infection on intervertebral disc degeneration and modic changes (MC) …

Study design. Animal laboratory study Objective. This study investigated the effects of C.
acnes and S. epidermidis on the lumbar discs of rabbits, as well as the outcomes of …

A 40-year-old woman with a history of chronic low back pain underwent a fluoroscopically
guided intradiscal platelet-rich plasma injection (PRP) at the L5–S1 level. She subsequently …

Background The contribution of Cutibacterium acnes (C. acnes) infection to intervertebral
disc degeneration (IDD) and the antibiotic therapy has evoked several controversies in …

Lumbar disc degeneration (LDD) and low back pain (LBP) are two conditions that are
closely related. Several studies have shown Cutibacterium acnes colonization of …

Study Design. A case-control study of animal model of Modic changes (MCs) on rabbits.
Objective. To evaluate the feasibility of inducing of MCs by injection of Propionibacterium …