OBJECTIVE: To describe women diagnosed with cervical intraepithelial neoplasia-grade 3
(CIN-3) diagnosed over the 2-year duration of the atypical squamous cells of undetermined …

Abstract The newly introduced Bethesda System proposes to replace the terms dysplasia,
carcinoma in situ (CIS), or cervical intraepithelial neoplasia (CIN) with two terms, low-grade …

The American Society for Colposcopy and Cervical Pathology sponsored a consensus
conference in 2001 to develop evidence-based guidelines for women with histologic …

Controversy exists in the United States regarding the proper evaluation and management of
low-grade squamous intraepithelial lesion (LSIL) and equivocal (atypical squamous cells of …

Background Histomorphological grading of cervical intraepithelial neoplasia (CIN) is crucial
for clinical management. CIN grading is however subjective and affected by substantial rates …

There are two major issues that need to be addressed by the health care professional
treating patients who demonstrate cellular abnormalities on screening cytology. First, the …

Context.—The correct diagnosis and reporting of cervical in situ and invasive carcinoma are
essential for the appropriate clinical management of patients with human papillomavirus …

Abstract “Atypical squamous cells, cannot exclude a high‐grade squamous intraepithelial
lesion (ASC‐H)” is a new diagnostic category in the 2001 Bethesda nomenclature system for …

For every 100,000 women in the United States, eight new cervical cancer cases and two
deaths are reported as per the most recent (2017) Center of Disease Control and Prevention …

Context.—Lower Anogenital Squamous Terminology (LAST) standardization recommended
p16INK4a immunohistochemistry (p16 IHC) for biopsies diagnosed morphologically as …