OBJECTIVE To discuss the epidemiology, pathogenesis, diagnosis, expected course,
prognosis, and treatment of amyotrophic lateral sclerosis (ALS), a degenerative disorder of …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease associated
with a life expectancy of approximately 3 years after symptom onset, but the range of survival …

It is now possible to slow the disease progression of amyotrophic lateral sclerosis (ALS), but
documented improvement in the quality of life of ALS patients has been difficult to quantitate …

Objectives: To continuously assess overall quality of life (QOL) and disease progression in
patients with amyotrophic lateral sclerosis (ALS) at different stages of the disease and …

Amyotrophic lateral sclerosis (ALS) is not a curable disease, but it is treatable. By definition,
much of the care provided to ALS patients is palliative, even though active life-sustaining …

Death represents the main hallmark of amyotrophic lateral sclerosis (ALS). Despite its
importance in clinical care and phase III trials, many uncertainties remain on the cause of …

Amyotrophic lateral sclerosis (ALS) is the most common form of degenerative motor neuron
disease in adulthood. The clinical picture was accurately described by Charcot over 125 …