Magnesium ions (Mg2+) are widely present in biological fluids, and they are suggested as
the vital factors that inhibit spontaneous hydroxyapatite (HAP) precipitation in nature …

It has long been known that magnesium (Mg) ions are effective inhibitors of hydroxyapatite
(HAP) crystal nucleation and growth. During the HAP nucleation, it is now generally …

Calcium phosphates are one of the most important biogenic minerals found in living
organisms. Recent studies have suggested a non-classical mineralization pathway, which …

Non-collagenous proteins (NCPs) inhibit hydroxyapatite (HA; Ca5 (PO4) 3OH) formation in
living organisms by binding to nascent nuclei of HA and preventing their further growth …

Generally, a solution nucleation model is used to study biomineralization kinetics. However,
we found that the amorphous calcium phosphate (ACP)-mediated hydroxyapatite (HAP) …

Polar and charged amino acids (AAs) are heavily expressed in non-collagenous proteins
(NCPs), and are involved in hydroxyapatite (HA) mineralization in bone. Here, we review …

Crystallization via phase transformation of a metastable precursor is a ubiquitous and
effective strategy used by living systems to direct the growth of crystalline nanomaterials with …

Hydroxyapatite (HAp) is a major inorganic component in bone minerals and is often used for
bone tissue engineering. Herein, we synthesized HAp using sebacic acid as an additive at …

Although phase transformation is suggested as a key step in biomineralization, the chemical
scenario about how organic molecules mediate inorganic phase transformations is still …

Amorphous calcium phosphate (ACP) is an important intermediate phase during the
biomineralization of apatite. But the detailed mechanism of transformation from ACP to …