Cholesterol efflux from macrophages is the first step of reverse cholesterol transport (RCT),
whose increase inhibits cholesterol accumulation and foam cell formation to suppress …

As the most abundant flavonoid in Ampelopsis grossedentata, the protective effects of
dihydromyricetin on atherosclerosis have been well established, yet the detailed …

The accumulation of foam cells in atherosclerotic lesions is a hallmark of early-stage
atherosclerosis. Kaempferol has been shown to inhibit oxidized low-density lipoprotein …

Berberine, a botanical alkaloid purified from Cortidis rhizoma, has effects in cardiovascular
diseases, yet the mechanism is not fully understood. Foam cells play a critical role in the …

Introduction: Atherosclerosis is the main cause of many cardiovascular diseases and
contributes to morbidity and mortality worldwide. The formation of macrophage-derived foam …

Cholesterol deposition in intimal macrophages leads to foam cell formation and
atherosclerosis. Reverse cholesterol transport (RCT), initiated by efflux of excess cholesterol …

The accumulation of cholesterol in macrophages could induce the formation of foam cells
and increase the risk of developing atherosclerosis. We wonder if quercetin, one of …

Context: Chrysin, a natural flavonoid, has been shown to possess multiple pharmacological
activities including anti-atherosclerosis. Objective: The effects of chrysin on foam cell …

To investigate the effects of neopterin on ABCA1 expression and cholesterol efflux in human
THP-1 macrophage-derived foam cells, and to explore the role of the liver X receptor alpha …

Allicin is considered anti-atherosclerotic due to its antioxidant and anti-inflammatory effects,
which makes it an important drug for the prevention and treatment of atherosclerosis …