Emerging roles of microRNA in the intracellular signaling networks of hepatocellular carcinoma

PTY Law, N Wong - Journal of gastroenterology and …, 2011 - Wiley Online Library
MicroRNAs (miRNAs) are small non‐coding RNAs of 19–23 nucleotides that negatively
regulate gene expression through binding to the 3′‐untranslated regions of target …

MicroRNAs in hepatocellular carcinoma: regulation, function, and clinical implications

J Sun, H Lu, X Wang, H Jin - The Scientific World Journal, 2013 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and the
third cause of cancer‐related death. Poor understanding of the mechanisms underlying the …

[HTML][HTML] The role of micro-RNAs in hepatocellular carcinoma: from molecular biology to treatment

M D'Anzeo, L Faloppi, M Scartozzi, R Giampieri… - Molecules, 2014 - mdpi.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third
leading cause of cancer deaths. microRNAs (miRNAs) are evolutionary conserved small …

[HTML][HTML] MicroRNAs in the pathogenesis of hepatocellular carcinoma: A review

A Morishita, K Oura, T Tadokoro, K Fujita, J Tani… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

[HTML][HTML] Function and clinical potential of microRNAs in hepatocellular carcinoma

L Wang, Y Yue, X Wang, H Jin - Oncology letters, 2015 - spandidos-publications.com
MicroRNAs (miRNAs) are small non‑coding RNAs involved in the initiation and progression
of several types of human cancer, including hepatocellular carcinoma (HCC), which is one …

[HTML][HTML] Molecular and functional roles of microRNAs in the progression of hepatocellular carcinoma—a review

K Oura, A Morishita, T Masaki - International Journal of Molecular …, 2020 - mdpi.com
Liver cancer is the fourth leading cause of cancer deaths globally, of which hepatocellular
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …

Cancer-related microRNAs and their role as tumor suppressors and oncogenes in hepatocellular carcinoma

L Gailhouste, T Ochiya - 2013 - digitum.um.es
MicroRNAs (miRNAs) have emerged as key factors involved in several biological processes,
including development, differentiation, cell proliferation, and tumorigenesis. In …

microRNA: a promising diagnostic biomarker and therapeutic target for hepatocellular carcinoma

X Li, W Yang, L Lou, Y Chen, S Wu, G Ding - Digestive diseases and …, 2014 - Springer
Abstract microRNAs constitute a novel class of small, non-coding RNAs that negatively
regulate gene expression via translational inhibition or mRNA degradation. Aberrant miRNA …

[HTML][HTML] miRNAs affect the development of hepatocellular carcinoma via dysregulation of their biogenesis and expression

R Chu, G Mo, Z Duan, M Huang, J Chang, X Li… - Cell Communication and …, 2014 - Springer
The pathogenesis of hepatocellular carcinoma (HCC) is not fully understood, which has
affected the early diagnosis and treatment of HCC and the survival time of patients …

Involvement of microRNAs and their potential diagnostic, therapeutic, and prognostic role in hepatocellular carcinoma

Y Zhou, F Liu, C Ma, Q Cheng - Journal of Clinical Laboratory …, 2022 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) accounts for 85%–90% of primary liver
cancer. MicroRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression by …