CD40 and its ligand in atherosclerosis
CD40-CD40 ligand (CD40L) interactions play a central role in the development and
progression of atherosclerosis. In the late 1990s, we and others have shown that complete …
progression of atherosclerosis. In the late 1990s, we and others have shown that complete …
The CD40-CD40 ligand system: a potential therapeutic target in atherosclerosis.
Atherosclerosis is a leading cause of cardiovascular disease in the westernized world. This
review highlights emerging evidence linking atherosclerosis to the CD40-CD40 ligand …
review highlights emerging evidence linking atherosclerosis to the CD40-CD40 ligand …
CD40-CD40L interactions in atherosclerosis
E Lutgens, MJAP Daemen - Trends in cardiovascular medicine, 2002 - Elsevier
Increasing evidence supports a central role for CD40–CD40L interactions in the
pathogenesis of atherosclerosis. Recently, we have shown that CD40L deficiency as well as …
pathogenesis of atherosclerosis. Recently, we have shown that CD40L deficiency as well as …
CD40 and vascular inflammation.
C Urbich, S Dimmeler - The Canadian journal of cardiology, 2004 - europepmc.org
Atherosclerosis is currently considered a chronic inflammatory disease combined with a
disorder of lipid metabolism and deposition. Risk factors for coronary disease, as well as …
disorder of lipid metabolism and deposition. Risk factors for coronary disease, as well as …
CD40 signaling and plaque instability
U Schönbeck, P Libby - Circulation research, 2001 - Am Heart Assoc
Today, multiple lines of evidence support the view of atherosclerosis as a chronic
inflammatory disease and implicate components of the immune system in atherogenesis …
inflammatory disease and implicate components of the immune system in atherogenesis …
The CD40-CD40L system in cardiovascular disease
Abstract The CD40-CD40L system is a pathway which is associated with both prothrombotic
and proinflammatory effects. CD40 and its ligand were first discovered on the surface of …
and proinflammatory effects. CD40 and its ligand were first discovered on the surface of …
CD40 ligand is selectively expressed on CD4+ T cells and platelets: implications for CD40–CD40L signalling in atherosclerosis
K Büchner, V Henn, M Gräfe, OJ de Boer… - The Journal of …, 2003 - Wiley Online Library
Atherosclerosis is a degenerative inflammatory disease of the vascular system. Endothelial
cells (ECs), smooth muscle cells, and macrophages, key elements in atherosclerosis, all …
cells (ECs), smooth muscle cells, and macrophages, key elements in atherosclerosis, all …
Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40–CD40 ligand signaling in …
F Mach, U Schönbeck, GK Sukhova… - Proceedings of the …, 1997 - National Acad Sciences
Increasing evidence supports involvement of inflammation and immunity in atherogenesis.
We report here that CD40 ligand (CD40L), an immunoregulatory signaling molecule …
We report here that CD40 ligand (CD40L), an immunoregulatory signaling molecule …
The CD40/CD40 ligand system: linking inflammation with atherothrombosis
C Antoniades, C Bakogiannis, D Tousoulis… - Journal of the American …, 2009 - jacc.org
The role of CD40/CD40 ligand (CD40L) in atherothrombosis is now widely accepted.
However, the exact mechanisms linking the CD40/CD40L system and the soluble form of …
However, the exact mechanisms linking the CD40/CD40L system and the soluble form of …
CD40 signaling in vascular cells: a key role in atherosclerosis?
F Mach, U Schönbeck, P Libby - Atherosclerosis, 1998 - Elsevier
Atherosclerosis is one of the most prevalent fatal diseases in Western societies, and results
from an intricate interplay between diverse factors such as lipid metabolism, blood …
from an intricate interplay between diverse factors such as lipid metabolism, blood …