Early identification of high-risk disease could greatly reduce both mortality and morbidity due
to oral cancer. We describe a simple handheld device that facilitates the direct visualization …

Background: We report the results of a clinical in vivo study to evaluate the potential of
fluorescence spectroscopy for differential diagnosis of oral mucosal malignant and …

Objective To evaluate the clinical potential of fluorescence spectroscopy (a noninvasive
technique for assessing the chemical and morphologic composition of tissue) for in vivo …

Oral cancer is a significant health problem in the USA and throughout the world. Most oral
cancer patients are diagnosed at a late stage, when treatment is less successful and …

Autofluorescence (AF) and diffuse reflectance (DR) spectroscopic techniques have shown
good diagnostic accuracies for noninvasive detection of oral cavity cancer. In the present …

Autofluorescence spectroscopy shows promising results for detection and staging of oral
(pre-) malignancies. To improve staging reliability, we develop and compare algorithms for …

The aim is to evaluate the accuracy of autofluorescence for screening oral cancer in
comparison with toluidine blue staining and clinical examination. Oral mucosal disorders …

Purpose: Autofluorescence imaging is increasingly used to noninvasively identify neoplastic
oral cavity lesions. Improving the diagnostic accuracy of these techniques requires a better …

Autofluorescence spectroscopy and imaging have been studied for the early detection and
classification of (pre) malignancies of the oral mucosa. In the present review we will give an …

Background Oral cancer is a serious global issue and early diagnosis of oral cancer is the
key in reducing the high mortality rate. Autofluorescence properties of oral mucosa have …