Hypoxic postconditioning activates the Wnt/β‐catenin pathway and protects against transient global cerebral ischemia through Dkk1 inhibition and GSK‐3β …
L Zhan, D Liu, H Wen, J Hu, T Pang, W Sun… - The FASEB …, 2019 - Wiley Online Library
ABSTRACT The Wingless/Int (Wnt)/β‐catenin pathway plays an essential role in cell
survival. Although post‐conditioning with 8% oxygen can alleviate transient global cerebral …
survival. Although post‐conditioning with 8% oxygen can alleviate transient global cerebral …
Stabilization of nuclear β‐catenin by inhibiting KDM2A mediates cerebral ischemic tolerance
Y Zuo, L Zhan, H Wen, J Xue, Y Tan, W Sun… - The FASEB …, 2023 - Wiley Online Library
Abstract Hypoxic postconditioning (HPC) with 8% oxygen increases nuclear accumulation of
β‐catenin through activating the classical Wnt pathway, thereby alleviating transient global …
β‐catenin through activating the classical Wnt pathway, thereby alleviating transient global …
Phosphorylation of p38 MAPK mediates hypoxic preconditioning-induced neuroprotection against cerebral ischemic injury via mitochondria translocation of Bcl-xL in …
L Zhao, X Liu, J Liang, S Han, Y Wang, Y Yin, Y Luo… - Brain research, 2013 - Elsevier
Hypoxic preconditioning (HPC) initiates intracellular signaling pathway to provide protection,
but the role of p38 mitogen-activated protein kinase (p38 MAPK) in HPC-induced …
but the role of p38 mitogen-activated protein kinase (p38 MAPK) in HPC-induced …
Hypoxic preconditioning attenuates neuronal cell death by preventing MEK/ERK signaling pathway activation after transient global cerebral ischemia in adult rats
L Zhan, H Yan, H Zhou, W Sun, Q Hou, E Xu - Molecular neurobiology, 2013 - Springer
Our previous data indicated that hypoxic preconditioning (HPC) ameliorates transient global
cerebral ischemia (tGCI)-induced neuronal death in hippocampal CA1 subregion of adult …
cerebral ischemia (tGCI)-induced neuronal death in hippocampal CA1 subregion of adult …
cPKCγ-modulated autophagy in neurons alleviates ischemic injury in brain of mice with ischemic stroke through Akt-mTOR pathway
We have reported that neuron-specific conventional protein kinase C (cPKC) γ is involved in
the development of cerebral hypoxic preconditioning (HPC) and the neuroprotection against …
the development of cerebral hypoxic preconditioning (HPC) and the neuroprotection against …
cPKCγ-Modulated Autophagy Contributes to Ischemic Preconditioning–Induced Neuroprotection in Mice with Ischemic Stroke via mTOR-ULK1 Pathway
Y Zhang, L Ma, Y Yan, L Zhao, S Han, D Wu… - Translational stroke …, 2023 - Springer
Neuron-specific conventional protein kinase C (cPKC) γ mediates cerebral hypoxic
preconditioning (HPC). In parallel, autophagy plays a prosurvival role in ischemic …
preconditioning (HPC). In parallel, autophagy plays a prosurvival role in ischemic …
[HTML][HTML] Hypoxic postconditioning‑induced neuroprotection increases neuronal autophagy via activation of the SIRT1/FoxO1 signaling pathway in rats with global …
J Liu, Z Gong, J Wu, S Liu, X Wang… - Experimental and …, 2021 - spandidos-publications.com
Hypoxic postconditioning (HPC) has been reported to be a beneficial and promising
treatment for global cerebral ischemia (GCI). However, its neuroprotective mechanism …
treatment for global cerebral ischemia (GCI). However, its neuroprotective mechanism …
Determination of brain-regional blood perfusion and endogenous cPKCγ impact on ischemic vulnerability of mice with global ischemia
S Liu, Q Dai, R Hua, T Liu, S Han, S Li, J Li - Neurochemical Research, 2017 - Springer
Conventional protein kinase C (cPKC) γ participated in cerebral hypoxic preconditioning-
induced neuroprotection and affected the neurological outcome of ischemic stroked mice. As …
induced neuroprotection and affected the neurological outcome of ischemic stroked mice. As …
Hypoxic Preconditioning Attenuates Neuroinflammation via Inhibiting NF-κB/NLRP3 Axis Mediated by p-MLKL after Transient Global Cerebral Ischemia
X Lu, L Zhan, G Chai, M Chen, W Sun, E Xu - Molecular Neurobiology, 2024 - Springer
Hypoxic preconditioning (HPC) has been reported to alleviate neuronal damage and
microglial activation in hippocampal CA1 after transient global cerebral ischemia (tGCI) …
microglial activation in hippocampal CA1 after transient global cerebral ischemia (tGCI) …
The roles of p38 MAPK/MSK1 signaling pathway in the neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in adult rats
P Zhu, L Zhan, T Zhu, D Liang, J Hu, W Sun… - Molecular …, 2014 - Springer
Postconditioning has regenerated interest as a mechanical intervention against cerebral
ischemia/reperfusion injury, but its molecular mechanisms remain unknown. We previously …
ischemia/reperfusion injury, but its molecular mechanisms remain unknown. We previously …
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