The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability,
gastrointestinal side effects, first-pass metabolism and P-glycoprotein efflux pumps. Thus …

Introduction: Docetaxel (DTX) has been proven as one of the most important cytotoxic
agents, and its clinical efcacy against many cancers is superior to paclitaxel. DTX in …

Introduction: Docetaxel (DTX) is one of the most important chemotherapeutic agents and has
been widely used for treatment of various types of cancers. However, the clinical …

Docetaxel has been recognized as one of the most efficient anticancer drugs over the past
decade; however, its poor water solubility and systemic toxicity have greatly limited its …

Simple Summary As lung cancer has the highest incidence rate compared to any other type
of cancer, there have been extensive research studies aiming at finding a better treatment …

The clinical dosage formulation of Paclitaxel and Docetaxel, Taxol® and Taxotere®, while
having high efficacy, can cause serious side effects due to the adjuvant used. We have …

Docetaxel (DTX) is a chemotherapeutic drug with poor hydrophilicity and permeability. Its
lipophilic properties decrease its absorption in systemic circulation which hinders its …

A growing interest in the use of a combination of chemosensitizers and cytostatics for
overcoming cancer resistance to treatment and the development of their delivery systems …

Amongst the various microtubule-targeting agents, Docetaxel (DTX) has gained immense
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …

Nanoxel-PM™, docetaxel-loaded methoxy-poly (ethylene glycol)-block-poly (d, l-
lactide)(mPEG-PDLLA) micellar formulation was prepared in an effort to develop alternative …