The failure rate for vascular interventions (vein bypass grafting, arterial angioplasty/stenting)
remains unacceptably high. Over the past two decades, researchers have applied a wide …

Tumors exploit angiogenesis, the formation of new blood vessels from pre-existing
vasculature, in order to obtain nutrients required for continued growth and proliferation …

The extracellular matrix plays a critical role in orchestrating the events necessary for wound
healing, muscle repair, morphogenesis, new blood vessel growth, and cancer invasion. In …

Tumor growth and progression are critically dependent on the establishment of a vascular
support system. This is often accomplished via the expression of pro-angiogenic growth …

Constitutive expression of VEGF after implantation of genetically engineered myoblasts into
non-ischemic muscle led to an increase in vascular structures. Previously, effects of VEGF …

Neointimal hyperplasia is amongst the major causes of failure of bypass grafts. The disease
progression varies from patient to patient due to a range of different factors. In this paper, a …

Vascular endothelial growth factor (VEGF) plays a critical role in angiogenesis and has been
applied to medical therapy. However, because vascular imaging at the molecular level is …

Over the past two decades, a number of mathematical and computational models have been
developed to study different aspects of angiogenesis that span the spatial and temporal …

Convective transport can significantly distort spatial concentration gradients. Interstitial flow
is ubiquitous throughout living tissue, but our understanding of how interstitial flow affects …

Background Angiogenesis, a process of generation of new blood vessels from the pre-
existing vasculature, has been demonstrated to be a basic prerequisite for sustainable …