Vascular endothelial growth factor-induced migration of vascular smooth muscle cells in vitro
CL Grosskreutz, B Anand-Apte, C Dupláa… - Microvascular …, 1999 - Elsevier
Angiogenesis is a complex process that includes recruitment and proliferation of mural cells—
smooth muscle cells (SMC) and pericytes. Vascular endothelial growth factor (VEGF) has …
smooth muscle cells (SMC) and pericytes. Vascular endothelial growth factor (VEGF) has …
VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses
TT Rissanen, JE Markkanen, M Gruchala… - Circulation …, 2003 - Am Heart Assoc
Optimal angiogenic and lymphangiogenic gene therapy requires knowledge of the best
growth factors for each purpose. We studied the therapeutic potential of human vascular …
growth factors for each purpose. We studied the therapeutic potential of human vascular …
Mathematical modeling of tumor-induced angiogenesis
MAJ Chaplain, SR McDougall… - Annu. Rev. Biomed …, 2006 - annualreviews.org
Angiogenesis, the growth of a network of blood vessels, is a crucial component of solid
tumor growth, linking the relatively harmless avascular and the potentially fatal vascular …
tumor growth, linking the relatively harmless avascular and the potentially fatal vascular …
Model of competitive binding of vascular endothelial growth factor and placental growth factor to VEGF receptors on endothelial cells
F Mac Gabhann, AS Popel - American Journal of …, 2004 - journals.physiology.org
Placental growth factor (PlGF) competes with vascular endothelial growth factor (VEGF) for
binding to VEGF receptor (VEGFR)-1 but does not bind VEGFR2. Experiments show that …
binding to VEGF receptor (VEGFR)-1 but does not bind VEGFR2. Experiments show that …
The role of the microvascular network structure on diffusion and consumption of anticancer drugs
P Mascheroni, R Penta - International journal for numerical …, 2017 - Wiley Online Library
We investigate the impact of microvascular geometry on the transport of drugs in solid
tumors, focusing on the diffusion and consumption phenomena. We embrace recent …
tumors, focusing on the diffusion and consumption phenomena. We embrace recent …
Restoration of blood flow and evaluation of corresponding angiogenic events by scanning electron microscopy after a single dose of VEGF in a model of peripheral …
T Kofidis, D Nolte, AR Simon, A Metzakis, L Balsam… - Angiogenesis, 2002 - Springer
The angiogenic effect of vascular endothelial growth factor (VEGF) has typically been
assessed by indirect methods, including microsphere injection and angiography. Here, we …
assessed by indirect methods, including microsphere injection and angiography. Here, we …
Microenvironmental VEGF distribution is critical for stable and functional vessel growth in ischemia
G Von Degenfeld, A Banfi, ML Springer… - The FASEB …, 2006 - Wiley Online Library
The critical role of vascular endothelial growth factor (VEGF) expression levels in
developmental angiogenesis is well established. Nonetheless, the effects of different local …
developmental angiogenesis is well established. Nonetheless, the effects of different local …
Combining in silico and in vitro models to inform cell seeding strategies in tissue engineering
R Coy, G Al-Badri, C Kayal… - Journal of the …, 2020 - royalsocietypublishing.org
The seeding density of therapeutic cells in engineered tissue impacts both cell survival and
vascularization. Excessively high seeded cell densities can result in increased death and …
vascularization. Excessively high seeded cell densities can result in increased death and …
Blood flow can signal during angiogenesis not only through mechanotransduction, but also by affecting growth factor distribution
Growth factors, such as VEGF, promote the sprouting of new blood vessels. Growth factors
are generally produced far from the endothelium, and the transport of these proteins is often …
are generally produced far from the endothelium, and the transport of these proteins is often …
Computational models of sprouting angiogenesis and cell migration: towards multiscale mechanochemical models of angiogenesis
TAM Heck, MM Vaeyens… - … Modelling of Natural …, 2015 - mmnp-journal.org
Angiogenesis, the formation of new bloods vessels from the existing vasculature, is a
process that is essential during development and regeneration of tissues, and that plays a …
process that is essential during development and regeneration of tissues, and that plays a …