Over the last decade, nanotherapeutics gained increasingly important role in drug delivery
because of their frequently beneficial pharmacokinetics (PK) and lower toxicity when …

Angiogenesis, the formation of new blood vessels sprouting from existing ones, occurs in
several situations like wound healing, tissue remodeling, and near growing tumors. Under …

EDITORIAL published: 13 September 2013 doi: 10.3389/fonc. 2013.00233 stem cells in
endometrial cancer. Jain and Jackson ( 4) present a hybrid model that simulates the …

Although the angiogenic effect of vascular endothelial growth factor (VEGF) is widely
recognized, a central question concerns whether the vessels formed on its overexpression …

An algorithm is presented for solving a diffusion equation on a curved surface coupled to
diffusion in the volume, a problem often arising in cell biology. It applies to pixilated surfaces …

Spatial models of vascularized tissues are widely used in computational physiology. We
introduce a software library for composing multiscale, multiphysics models for applications …

Quantitative descriptions of transport and exchange in physiological systems should make
use of the emerging wealth of data on vascular anatomic structure. These descriptions may …

Therapeutic angiogenesis by vascular endothelial growth factor (VEGF) gene delivery is an
attractive approach to treat ischemia. VEGF remains localized around each producing cell in …

The widespread incidence of cardiovascular diseases and associated mortality and
morbidity, along with the advent of powerful computational resources, have fostered an …

When vein segments are implanted into the arterial system for use in arterial bypass grafting,
adaptation to the higher pressure and flow of the arterial system is accomplished thorough …