Antioxidant protection: a promising therapeutic intervention in neurodegenerative disease
Oxidative stress has been consistently linked to ageing-related neurodegenerative
diseases. Neurodegenerative diseases are characterized by progressive dysfunction and …
diseases. Neurodegenerative diseases are characterized by progressive dysfunction and …
[HTML][HTML] Antioxidant therapies for neurodegenerative diseases: mechanisms, current trends, and perspectives
DP Gelain, GA Behr, RB de Oliveira… - Oxidative medicine and …, 2012 - ncbi.nlm.nih.gov
Over the last decades, the involvement of free radicals and oxidative stress in the molecular
mechanisms related to ageing, cancer, atherosclerosis, neurodegenerative disorders …
mechanisms related to ageing, cancer, atherosclerosis, neurodegenerative disorders …
Antioxidants as treatment for neurodegenerative disorders
B Moosmann, C Behl - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Oxidative stress is a ubiquitously observed hallmark of neurodegenerative disorders.
Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …
Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …
Oxidative stress, antioxidants and neurodegenerative diseases
I Casetta, V Govoni, E Granieri - Current pharmaceutical design, 2005 - ingentaconnect.com
It is widely accepted that oxidative stress increases with age, and that age is a major risk
factor for several neurodegenerative diseases such as Parkinson's disease and Alzheimer's …
factor for several neurodegenerative diseases such as Parkinson's disease and Alzheimer's …
Neuroprotective effects of antioxidants in the management of neurodegenerative disorders: A literature review
Y Panahi, SM Rajaee, TP Johnston… - Journal of cellular …, 2019 - Wiley Online Library
It is proven that oxidative stress has a pivotal role in the process of neurodegeneration. The
use of antioxidants is an attractive method to prevent the incidence of neurodegenerative …
use of antioxidants is an attractive method to prevent the incidence of neurodegenerative …
Oxidative stress and natural antioxidant mechanisms: the role in neurodegeneration. From molecular mechanisms to therapeutic strategies
A Karpińska, G Gromadzka - Postepy higieny i medycyny …, 2013 - europepmc.org
A lot of evidence exists that oxidative stress is the primary cause of neurodegeneration.
Neurons are more susceptible to oxidative damage than other cells due to their high oxygen …
Neurons are more susceptible to oxidative damage than other cells due to their high oxygen …
The role of oxidative stress in neurodegenerative diseases and potential antioxidant therapies
P Sienes Bailo, E Llorente Martín… - … in Laboratory Medicine …, 2022 - degruyter.com
Objectives The central nervous system (CNS) is essential for homeostasis and controls the
physiological functions of the body. However, the biochemical characteristics of the CNS …
physiological functions of the body. However, the biochemical characteristics of the CNS …
[HTML][HTML] The role of oxidative stress in neurodegenerative diseases
Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …
Antioxidant strategies in protection against neurodegenerative disorders
The most common neurodegenerative diseases include Alzheimer's disease, Parkinson's
disease and stroke; they are devastating clinical problems which lack effective treatments …
disease and stroke; they are devastating clinical problems which lack effective treatments …
Antioxidant therapies for neuroprotection—A review
Although moderate concentrations of reactive oxygen species (ROS) and reactive nitrogen
species (RNS) are crucial for various physiological processes within the human body, their …
species (RNS) are crucial for various physiological processes within the human body, their …