Antioxidant protection: a promising therapeutic intervention in neurodegenerative disease

N Ghosh, R Ghosh, SC Mandal - Free Radical Research, 2011 - Taylor & Francis
Oxidative stress has been consistently linked to ageing-related neurodegenerative
diseases. Neurodegenerative diseases are characterized by progressive dysfunction and …

[HTML][HTML] Antioxidant therapies for neurodegenerative diseases: mechanisms, current trends, and perspectives

DP Gelain, GA Behr, RB de Oliveira… - Oxidative medicine and …, 2012 - ncbi.nlm.nih.gov
Over the last decades, the involvement of free radicals and oxidative stress in the molecular
mechanisms related to ageing, cancer, atherosclerosis, neurodegenerative disorders …

Antioxidants as treatment for neurodegenerative disorders

B Moosmann, C Behl - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Oxidative stress is a ubiquitously observed hallmark of neurodegenerative disorders.
Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …

Oxidative stress, antioxidants and neurodegenerative diseases

I Casetta, V Govoni, E Granieri - Current pharmaceutical design, 2005 - ingentaconnect.com
It is widely accepted that oxidative stress increases with age, and that age is a major risk
factor for several neurodegenerative diseases such as Parkinson's disease and Alzheimer's …

Neuroprotective effects of antioxidants in the management of neurodegenerative disorders: A literature review

Y Panahi, SM Rajaee, TP Johnston… - Journal of cellular …, 2019 - Wiley Online Library
It is proven that oxidative stress has a pivotal role in the process of neurodegeneration. The
use of antioxidants is an attractive method to prevent the incidence of neurodegenerative …

Oxidative stress and natural antioxidant mechanisms: the role in neurodegeneration. From molecular mechanisms to therapeutic strategies

A Karpińska, G Gromadzka - Postepy higieny i medycyny …, 2013 - europepmc.org
A lot of evidence exists that oxidative stress is the primary cause of neurodegeneration.
Neurons are more susceptible to oxidative damage than other cells due to their high oxygen …

The role of oxidative stress in neurodegenerative diseases and potential antioxidant therapies

P Sienes Bailo, E Llorente Martín… - … in Laboratory Medicine …, 2022 - degruyter.com
Objectives The central nervous system (CNS) is essential for homeostasis and controls the
physiological functions of the body. However, the biochemical characteristics of the CNS …

[HTML][HTML] The role of oxidative stress in neurodegenerative diseases

GH Kim, JE Kim, SJ Rhie, S Yoon - Experimental neurobiology, 2015 - ncbi.nlm.nih.gov
Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …

Antioxidant strategies in protection against neurodegenerative disorders

DX Tan, LC Manchester, R Sainz, JC Mayo… - Expert Opinion on …, 2003 - Taylor & Francis
The most common neurodegenerative diseases include Alzheimer's disease, Parkinson's
disease and stroke; they are devastating clinical problems which lack effective treatments …

Antioxidant therapies for neuroprotection—A review

RI Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2019 - mdpi.com
Although moderate concentrations of reactive oxygen species (ROS) and reactive nitrogen
species (RNS) are crucial for various physiological processes within the human body, their …