[HTML][HTML] Paternal low protein diet programs preimplantation embryo gene expression, fetal growth and skeletal development in mice
AJ Watkins, S Sirovica, B Stokes, M Isaacs… - … Et Biophysica Acta (BBA …, 2017 - Elsevier
Defining the mechanisms underlying the programming of early life growth is fundamental for
improving adult health and wellbeing. While the association between maternal diet, offspring …
improving adult health and wellbeing. While the association between maternal diet, offspring …
Metabolic induction and early responses of mouse blastocyst developmental programming following maternal low protein diet affecting life-long health
JJ Eckert, R Porter, AJ Watkins, E Burt, S Brooks… - PloS one, 2012 - journals.plos.org
Previously, we have shown that a maternal low protein diet, fed exclusively during the
preimplantation period of mouse development (Emb-LPD), is sufficient to induce by the …
preimplantation period of mouse development (Emb-LPD), is sufficient to induce by the …
Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice
AJ Watkins, KD Sinclair - American Journal of Physiology …, 2014 - journals.physiology.org
Although the association between maternal periconceptional diet and adult offspring health
is well characterised, our understanding of the impact of paternal nutrition at the time of …
is well characterised, our understanding of the impact of paternal nutrition at the time of …
Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension
WY Kwong, AE Wild, P Roberts, AC Willis… - …, 2000 - journals.biologists.com
Epidemiological studies have indicated that susceptibility of human adults to hypertension
and cardiovascular disease may result from intrauterine growth restriction and low birth …
and cardiovascular disease may result from intrauterine growth restriction and low birth …
Maternal periconceptional and gestational low protein diet affects mouse offspring growth, cardiovascular and adipose phenotype at 1 year of age
Human and animal studies have revealed a strong association between periconceptional
environmental factors, such as poor maternal diet, and an increased propensity for …
environmental factors, such as poor maternal diet, and an increased propensity for …
Do little embryos make big decisions? How maternal dietary protein restriction can permanently change an embryo's potential, affecting adult health
Periconceptional environment may influence embryo development, ultimately affecting adult
health. Here, we review the rodent model of maternal low-protein diet specifically during the …
health. Here, we review the rodent model of maternal low-protein diet specifically during the …
Maternal nutrition modifies trophoblast giant cell phenotype and fetal growth in mice
AJ Watkins, ES Lucas, S Marfy-Smith, N Bates… - …, 2015 - rep.bioscientifica.com
Mammalian placentation is dependent upon the action of trophoblast cells at the time of
implantation. Appropriate fetal growth, regulated by maternal nutrition and nutrient transport …
implantation. Appropriate fetal growth, regulated by maternal nutrition and nutrient transport …
Metabolic adaptations to early life protein restriction differ by offspring sex and post-weaning diet in the mouse
KW Whitaker, K Totoki, TM Reyes - Nutrition, Metabolism and …, 2012 - Elsevier
BACKGROUND AND AIMS: Low birth weight affects 1 in every 7 babies born globally and
can predict a lifetime of increased risk for adverse health outcomes, including cardiovascular …
can predict a lifetime of increased risk for adverse health outcomes, including cardiovascular …
The role of maternal nutrition during the periconceptional period and its effect on offspring phenotype
TP Fleming, JJ Eckert, O Denisenko - Periconception in physiology and …, 2017 - Springer
The early preimplantation embryo has been rigorously studied for decades to understand
inherent reproductive and developmental mechanisms driving its morphogenesis from …
inherent reproductive and developmental mechanisms driving its morphogenesis from …
Maternal low-protein diet alters hepatic lipid accumulation and gene expression related to glucose metabolism in young adult mouse offspring fed a postweaning high …
J Kim, A Choi, YH Kwon - Biochemical and biophysical research …, 2023 - Elsevier
Maternal consumption of low-protein (LP) diet during pregnancy has been demonstrated to
increase the chances of adult offspring developing metabolic syndrome, and this risk can be …
increase the chances of adult offspring developing metabolic syndrome, and this risk can be …
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