COPD is complex and there are multiple determinants of poor health, so most studies of
Chronic Obstructive Pulmonary Disease (COPD) now include health status, or health related …

Rationale: Chronic obstructive pulmonary disease (COPD) is thought to result in rapid and
progressive loss of lung function usually expressed as mean values for whole cohorts …

The severity of chronic obstructive pulmonary disease (COPD) and patients' response to
therapy are difficult to assess. The traditional measure, spirometry, correlates poorly with …

Rationale: Chronic obstructive pulmonary disease (COPD) can develop not only through a
lung function trajectory dominated by an accelerated decline of FEV1 from normal maximally …

Background Exacerbations affect morbidity in chronic obstructive pulmonary disease
(COPD). We sought to evaluate the association between exacerbation frequency and …

Rationale: Chronic obstructive pulmonary disease (COPD) seems to be a heterogeneous
disease with a variable course. Objectives: We wished to characterize the heterogeneity and …

Summary⇓ Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity
and mortality in the USA, and it remains one of the few diseases that continues to increase …

Purpose To quantify the relationship between severity of chronic obstructive pulmonary
disease (COPD) as expressed by Global Initiative for Chronic Obstructive Lung Disease …

Rationale There are no validated measures of disease activity in COPD. Since “active”
disease is expected to have worse outcomes (eg mortality), we explored potential markers of …

Chronic obstructive pulmonary disease (COPD) is a chronic airway inflammation
characterized by fixed airflow limitation and chronic respiratory symptoms, such as cough …