BACKGROUND & AIMS: Interferon-associated depression is a frequent side effect of
antiviral therapy for chronic hepatitis C. The aim of the present study was to investigate the …

Background Interferon alpha, used in hepatitis C virus (HCV) infection causes many
neuropsychiatric side effects: emotional disturbances, chronic fatigue, cognitive impairment …

Background: Psychiatric side effects are common during interferon-alfa (IFN-alfa) therapy
and often responsible for early treatment discontinuation, thus limiting its therapeutic …

Interferon (IFN) therapy has been associated with the development of Major Depressive
Disorder (MDD) when given to patients with hepatitis C (HCV). The incidence, time course …

Sleep disorder and psychotic symptoms have been reported in patients receiving
interferon(IFN). Insomnia and depressive mood emerged in about 30% and 17% of those …

Abstract Treatment of chronic hepatitis C with interferon alpha (IFN-·) is relatively
contraindicated in patients with psychiatric disorders because of possible severe psychiatric …

Background: Psychiatric side‐effects may require dose reduction or premature
discontinuation of interferon therapy in chronic hepatitis C. New strategies are needed in …

Objective: To determine whether individuals with concurrent active psychiatric disease and
chronic hepatitis C virus (HCV) can be treated safely and effectively with interferon-alpha …

BACKGROUND: Depression is considered the most frequent interferon (IFN)-α-induced
psychiatric disorder. However, other neuropsychiatric side effects of IFN treatment, such as …

The number of patients treated with interferon (IFN) has increased markedly in Japan since
1992, when the Health and Welfare Ministry approved the use of IFN for treating chronic …