Neuropsychiatric side-effects of interferon alfa therapy for hepatitis C and their management: a review

YR Al-Huthail - Saudi Journal of Gastroenterology, 2006 - journals.lww.com
Background: Interferon-Alfa (IFN-α) has been the mainstay of treatment for chronic hepatitis
C. It has the potential to alter the course of chronic hepatitis C and prevent complications …

Neuropsychiatric side effects of HCV therapy and their treatment: focus on IFNα-induced depression

P Hauser - Gastroenterology Clinics, 2004 - gastro.theclinics.com
Hepatologists and other health care providers are increasingly recognizing the need for a
systematic approach to managing hepatitis C virus (HCV) infection that takes into account …

Schizophrenic psychosis: a contraindication for treatment of hepatitis C with interferon alpha?

M Dobmeier, E Frick, S Frank, C Franke… - …, 2000 - thieme-connect.com
Depressive or psychotic symptoms are a well known side-effect of interferon alpha (INF-a).
Therefore, the questions arises whether a chronic psychosis should be considered a …

CASE REPORT Psychosis in a methadone‐substituted patient during interferon‐alpha treatment of hepatitis C

M Schäfer, T Boetsch, G Laakmann - Addiction, 2000 - Wiley Online Library
Interferon‐alpha (IFN‐α) is the only effective treatment for chronic hepatitis B and C. Over 2/3
of methadone‐substituted patients suffer from chronic hepatitis C but a history of psychiatric …

Psychosis associated with interferon alfa therapy for chronic hepatitis B

L Tamam, D Yerdelen… - Annals of …, 2003 - journals.sagepub.com
OBJECTIVE: To report a case of persistent psychosis that developed during interferon alfa
(IFN-α) therapy for chronic hepatitis B. CASE SUMMARY: A 26-year-old man who was …

A multidisciplinary therapeutic approach for reducing the risk of psychiatric side effects in patients with chronic hepatitis C treated with pegylated interferon α and …

S Neri, G Bertino, A Petralia, C Giancarlo… - Journal of clinical …, 2010 - journals.lww.com
Background Interferon-α is used to treat chronic hepatitis C. Interferons may induce adverse
events that usually, but not always, reverse within a few days after the end of therapy. Study …

Interferon-induced depression in hepatitis C: an update

B Keefe - Current psychiatry reports, 2007 - Springer
Hepatitis C is a global epidemic, and its costs in both lives and health care expenditures
continue to rise. The only approved treatment for this disease, interferonalpha (IFN), causes …

A quantitative assessment of depression and thyroid dysfunction secondary to interferon-α therapy in patients with hepatitis C

JM Loftis, JM Wall, E Linardatos, S Benvenga… - Journal of …, 2004 - Springer
The most effective treatment for hepatitis C virus (HCV) is interferon-a (IFN) therapy in
combination with ribavirin. Although symptoms of depression are among the most common …

Interferon-alpha-induced psychiatric side effects in patients with chronic viral hepatitis: a prospective, observational, controlled study

MG Orrù, A Baita, R Sitzia, A Costa… - Epidemiology and …, 2005 - cambridge.org
Aims—Patients with chronic viral hepatitis suffer from a high prevalence of psychiatric
problems. Furthermore, the treatment for chronic viral hepatitis, with interferon (IFN) alpha …

Managing the neuropsychiatric side effects of interferon-based therapy for hepatitis C.

CC Crone, GM Gabriel, TN Wise - Cleveland Clinic journal of …, 2004 - europepmc.org
Neuropsychiatric side effects are common with interferon-based therapy for chronic hepatitis
C, and their prompt recognition and management is essential to effective patient care …