Gestational chronodisruption impairs circadian physiology in rat male offspring, increasing the risk of chronic disease
Chronic exposure to light at night, as in shift work, alters biological clocks (chronodisruption),
negatively impacting pregnancy outcome in humans. Actually the interaction of maternal and …
negatively impacting pregnancy outcome in humans. Actually the interaction of maternal and …
Maternal circadian rhythms and the programming of adult health and disease
TJ Varcoe, KL Gatford… - American Journal of …, 2018 - journals.physiology.org
The in utero environment is inherently rhythmic, with the fetus subjected to circadian
changes in temperature, substrates, and various maternal hormones. Meanwhile, the fetus is …
changes in temperature, substrates, and various maternal hormones. Meanwhile, the fetus is …
Gestational chronodisruption leads to persistent changes in the rat fetal and adult adrenal clock and function
Key points Light at night is essential to a 24/7 society, but it has negative consequences on
health. Basically, light at night induces an alteration of our biological clocks, known as …
health. Basically, light at night induces an alteration of our biological clocks, known as …
Circadian rhythms in the fetus and newborn: significance of interactions with maternal physiology and the environment
M Serón-Ferré, HG Richter, GJ Valenzuela… - Prenatal and postnatal …, 2016 - Springer
Timing of balanced and precise daily delivery of oxygen, nutrients, hormones, and
biophysical cues from mother to fetus is essential for fetal growth and successful transition to …
biophysical cues from mother to fetus is essential for fetal growth and successful transition to …
Programming effects of maternal stress on the circadian system of adult offspring
Maternal stress has long-lasting influences on the brain functions of offspring, and several
brain regions have been proposed to mediate such programming. Although perinatal …
brain regions have been proposed to mediate such programming. Although perinatal …
Chronodisruption: An untimely cause of preterm birth?
Circadian rhythms, endogenous and entrainable adaptations to 24-hour cycles of light and
dark, influence almost all physiologic functions. Emerging evidence suggests that the …
dark, influence almost all physiologic functions. Emerging evidence suggests that the …
Light and circadian signaling pathway in pregnancy: Programming of adult health and disease
Light is a crucial environmental signal that affects elements of human health, including the
entrainment of circadian rhythms. A suboptimal environment during pregnancy can increase …
entrainment of circadian rhythms. A suboptimal environment during pregnancy can increase …
Environmental perturbation of the circadian clock disrupts pregnancy in the mouse
KC Summa, MH Vitaterna, FW Turek - PloS one, 2012 - journals.plos.org
Background The circadian clock has been linked to reproduction at many levels in
mammals. Epidemiological studies of female shift workers have reported increased rates of …
mammals. Epidemiological studies of female shift workers have reported increased rates of …
Timed maternal melatonin treatment reverses circadian disruption of the fetal adrenal clock imposed by exposure to constant light
N Mendez, L Abarzua-Catalan, N Vilches… - 2012 - journals.plos.org
Surprisingly, in our modern 24/7 society, there is scant information on the impact of
developmental chronodisruption like the one experienced by shift worker pregnant women …
developmental chronodisruption like the one experienced by shift worker pregnant women …
The impact of prenatal circadian rhythm disruption on pregnancy outcomes and long-term metabolic health of mice progeny
Animal studies demonstrate that circadian rhythm disruption during pregnancy can be
deleterious to reproductive capacity and the long-term health of the progeny. Our previous …
deleterious to reproductive capacity and the long-term health of the progeny. Our previous …
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