The 'obesity paradox'in atrial fibrillation: observations from the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) …

RK Sandhu, J Ezekowitz, U Andersson… - European heart …, 2016 - academic.oup.com
Aims The prognostic implication of adiposity on clinical outcomes in atrial fibrillation (AF)
patients treated with oral anticoagulation is unclear. Methods and results A total of 17 913 …

Current status and outcomes of direct oral anticoagulant use in real-world atrial fibrillation patients―fushimi AF registry―

Y Yamashita, R Uozumi, Y Hamatani, M Esato… - Circulation …, 2017 - jstage.jst.go.jp
Background: The current status and outcomes of direct oral anticoagulant (DOAC) use have
not been widely evaluated in unselected patients with atrial fibrillation (AF) in the real world …

[HTML][HTML] Effectiveness and safety of oral anticoagulants among NVAF patients with obesity: insights from the ARISTOPHANES study

S Deitelzweig, A Keshishian, A Kang… - Journal of Clinical …, 2020 - mdpi.com
This ARISTOPHANES analysis examined stroke/systemic embolism (SE) and major
bleeding (MB) among a subgroup of nonvalvular atrial fibrillation (NVAF) patients with …

The comparison of inappropriate-low-doses use among 4 direct oral anticoagulants in patients with atrial fibrillation: from the database of a single-center registry

T Sato, Y Aizawa, K Fuse, S Fujita, Y Ikeda… - Journal of Stroke and …, 2018 - Elsevier
Background Inappropriate doses of direct oral anticoagulants (DOACs) are often prescribed.
This study evaluated the prevalence, outcomes, and predictors of the prescription of …

Meta-analysis of direct-acting oral anticoagulants compared with warfarin in patients> 75 years of age

AH Malik, S Yandrapalli, WS Aronow, JA Panza… - The American journal of …, 2019 - Elsevier
Older patients with atrial fibrillation (AF) are at higher risk of thromboembolic events and oral
anticoagulant (OAC)-related bleeding complications. This meta-analysis evaluates the …

Inappropriate dosing of direct oral anticoagulants in patients with atrial fibrillation

A Sugrue, D Sanborn, M Amin, M Farwati… - The American journal of …, 2021 - Elsevier
Direct Oral Anticoagulants (DOACs) require dose adjustment based on specific patient
characteristics, making them prone to incorrect dosing. The current study aimed to evaluate …

Use of direct oral anticoagulants in morbidly obese patients

K Kido, JC Lee, T Hellwig… - … : The Journal of Human …, 2020 - Wiley Online Library
In 2016, the International Society on Thrombosis and Haemostasis (ISTH) published
guidelines advising caution when using direct oral anticoagulants (DOACs) in patients with …

Long-term risk of major adverse cardiac events in atrial fibrillation patients on direct oral anticoagulants

D Pastori, D Menichelli, F Del Sole, P Pignatelli… - Mayo Clinic …, 2021 - Elsevier
Objective To determine the association between direct oral anticoagulant (DOAC) use and
risk of major adverse cardiac events (MACEs) in patients with atrial fibrillation (AF). Patients …

Efficacy and safety of apixaban versus warfarin in patients with atrial fibrillation and extremes in body weight: insights from the ARISTOTLE trial

SH Hohnloser, M Fudim, JH Alexander, DM Wojdyla… - Circulation, 2019 - Am Heart Assoc
Background: Guidelines caution against the use of non–vitamin K antagonist oral
anticoagulants in patients with extremely high (> 120 kg) or low (≤ 60 kg) body weight …

Systematic review and adjusted indirect comparison meta-analysis of oral anticoagulants in atrial fibrillation

WL Baker, OJ Phung - Circulation: Cardiovascular Quality and …, 2012 - Am Heart Assoc
Background—Oral anticoagulants such as apixaban, dabigatran, and rivaroxaban are
alternatives to warfarin for preventing events in patients with atrial fibrillation. Direct …