Structure of plasma and tissue kallikreins
M Pathak, SS Wong, I Dreveny… - Thrombosis and …, 2013 - thieme-connect.com
The kallikrein kinin system (KKS) consists of serine proteases involved in the production of
peptides called kinins, principally bradykinin and Lys-bradykinin (kallidin). The KKS …
peptides called kinins, principally bradykinin and Lys-bradykinin (kallidin). The KKS …
Expression and characterization of human tissue kallikrein variants
H Chan, EB Springman, JM Clark - Protein expression and purification, 1998 - Elsevier
Human tissue kallikrein is a serine protease implicated in the pathology of various
inflammatory disorders. As one of the two principal enzymes that generate proinflammatory …
inflammatory disorders. As one of the two principal enzymes that generate proinflammatory …
The molecular biology of the kallikreins and their roles in inflammation
JA Clements - The kinin system, 1997 - Elsevier
Publisher Summary This chapter focuses primarily on the molecular biology of the tissue
kallikrein (KLK) gene family. The chapter emphasizes on the differences in gene structure …
kallikrein (KLK) gene family. The chapter emphasizes on the differences in gene structure …
Plasma kallikrein: the bradykinin-producing enzyme
J Björkqvist, A Jämsä, T Renné - Thrombosis and haemostasis, 2013 - thieme-connect.com
Plasma prekallikrein is the liver-derived precursor of the trypsin-like serine protease plasma
kallikrein (PK) and circulates in plasma bound to high molecular weight kininogen. The …
kallikrein (PK) and circulates in plasma bound to high molecular weight kininogen. The …
[HTML][HTML] Activation profiles and regulatory cascades of the human kallikrein-related peptidases
H Yoon, G Laxmikanthan, J Lee, SI Blaber… - Journal of biological …, 2007 - ASBMB
The human kallikrein (KLK)-related peptidases are the largest family of serine peptidases,
comprising 15 members (KLK1–15) and with the majority (KLK4–15) being identified only …
comprising 15 members (KLK1–15) and with the majority (KLK4–15) being identified only …
[引用][C] The Kallikrein‐Kinin System: Evolution of Form and Functiona
JM Conlon - Annals of the New York Academy of Sciences, 1998 - Wiley Online Library
The kallikrein–kinin system of mammals involves the sequential action of several well-
characterized proteolytic enzymes. 1, 2 Activation of Factor XII (Hageman factor) in blood at …
characterized proteolytic enzymes. 1, 2 Activation of Factor XII (Hageman factor) in blood at …
Substrate specificity of human kallikreins 1 and 6 determined by phage display
HX Li, BY Hwang, G Laxmikanthan, SI Blaber… - Protein …, 2008 - Wiley Online Library
The human tissue kallikrein (KLK) family contains 15 secreted serine proteases that are
expressed in a wide range of tissues and have been implicated in different physiological …
expressed in a wide range of tissues and have been implicated in different physiological …
[HTML][HTML] Molecular biology of tissue kallikrein.
RJ MAcDONALD, HS Margolius, EG Erdös - Biochemical Journal, 1988 - ncbi.nlm.nih.gov
Introduction Tissue kallikrein (or glandular kallikrein as it was called first) is a late bloomer.
Sixty-three years after its discovery in urine as a hypotensive material andhalf-a-century after …
Sixty-three years after its discovery in urine as a hypotensive material andhalf-a-century after …
Fifty years of research on the plasma kallikrein-kinin system: from protein structure and function to cell biology and in-vivo pathophysiology
IM Sainz, RA Pixley, RW Colman - Thrombosis and …, 2007 - thieme-connect.com
F or forty years my laboratory has been studying the kallikrein-kininogen-kinin system (KKS).
I was challenged by my mentor Dr. Sol Sherry in whose laboratory I was completing my …
I was challenged by my mentor Dr. Sol Sherry in whose laboratory I was completing my …
[HTML][HTML] Substrate specificity and inhibition of human kallikrein-related peptidase 3 (KLK3 or PSA) activated with sodium citrate and glycosaminoglycans
We report the enzymatic properties and substrate specificity of human recombinant KLK3 in
the presence of glycosaminoglycans (GAGs) and sodium citrate. This salt is highly …
the presence of glycosaminoglycans (GAGs) and sodium citrate. This salt is highly …