Risk of a first venous thrombotic event in carriers of a familial thrombophilic defect. The European Prospective Cohort on Thrombophilia (EPCOT)

CY Vossen, J Conard, J Fontcuberta… - … of Thrombosis and …, 2005 - Wiley Online Library
Background: Reliable risk estimates for venous thrombosis in families with inherited
thrombophilia are scarce but necessary for determining optimal screening and treatment …

Thrombophilia and its impact on pregnancy

I Pabinger - Thrombosis research, 2009 - Elsevier
In recent years thrombophilia has gained much attention as a risk factor for pregnancy
complications. Whereas there is an established correlation between antiphospholipid …

Thrombophilia in pregnancy

ID Walker - Journal of clinical pathology, 2000 - jcp.bmj.com
Thrombophilia can be defined as a predisposition to thrombosis. Abnormalities in
haemostasis that are associated with clinical thrombophilia include heritable defects, such …

Thrombophilia, risk factors and prevention

E Campello, L Spiezia, A Adamo… - Expert review of …, 2019 - Taylor & Francis
Introduction: Fifty-three years after the first description of an inherited prothrombotic
condition (antithrombin deficiency), our knowledge on hereditary and acquired causes of …

Thrombophilia and venous thromboembolism: implications for testing

DM Cohn, S Roshani… - Seminars in thrombosis …, 2007 - thieme-connect.com
In the last decades, the knowledge on the etiology of venous thromboembolism (VTE) has
increased tremendously. In approximately half of patients presenting with VTE, one or more …

Inherited thrombophilia in arterial disease: a selective review

P de Moerloose, F Boehlen - Seminars in hematology, 2007 - Elsevier
Thrombophilia may be defined as an acquired or congenital abnormality of hemostasis
predisposing to thrombosis. Because arterial thrombosis is usually linked with classical risk …

ACOG Practice Bulletin No. 197: inherited thrombophilias in pregnancy

American College of Obstetricians … - Obstetrics and …, 2018 - pubmed.ncbi.nlm.nih.gov
Inherited thrombophilias are associated with an increased risk of venous thromboembolism
and have been linked to adverse outcomes in pregnancy. However, there is limited …

[HTML][HTML] Family history and inherited thrombophilia

GL Van Sluis, M Söhne, DY El Kheir, MW Tanck… - Journal of Thrombosis …, 2006 - Elsevier
Background: It is a common belief that patients with venous thrombosis and a positive family
history for venous thromboembolism (VTE) have an increased likelihood of having an …

Pros and cons of thrombophilia testing: pros

I Martinelli - Journal of Thrombosis and Haemostasis, 2003 - jthjournal.org
Unlike the deficiencies of the anticoagulant proteins antithrombin, protein C and S, rare in
patients with venous thromboembolism (VTE; 5% altogether) and in the general population …

Screening and management of inherited thrombophilias in the setting of adverse pregnancy outcome

MJ Paidas, DHW Ku, YS Arkel - Clinics in perinatology, 2004 - perinatology.theclinics.com
Inherited thrombophilias are a heterogeneous group of conditions whose natural history
continues to evolve. A decade ago, the most commonly identified inherited thrombophilias …