Norepinephrine, isoproterenol, insulin, and glucagon increase the type II (low Km)
iodothyronine 5'-deiodinase (5'-D) in the brown adipose tissue (BAT) of intact rats …

Thyroxine (T4) and reverse triiodothyronine are potent inhibitors of brown adipose T4 5'-
deiodinase (BAT 5'D). This effect does not require protein synthesis and is due to an …

Iodothyronine type II 5'-deiodinase (5'D-II) activities were studied in cultures of rat brown
adipocytes. In the presence of serum, the adrenergically stimulated 5'D-II activities were very …

Thyroxine 5'-deiodinase (type II) is present in a microsomal fraction of brown adipose tissue
(BAT) of Syrian hamsters. Cold exposure increased specific activity in homogenates after a …

We examined type II 5'-iodothyronine deiodinase activation by adrenergic agonists in
dispersed brown adipocytes from euthyroid and hypothyroid rats. In euthyroid cells, basal …

We describe an in vitro system for evaluating the direct effects of catecholamines on the
activity of the type II iodothyronine 5'-deiodinase in dispersed rat brown adipocytes …

Previous studies have shown that norepinephrine causes a marked increase in the
iodothyronine 5′-deiodinase activity in dispersed brown adipocytes. This stimulation …

However, the metabolism of TH in white adipose tissue is poorly characterized. Our
objective was to describe possible changes in activities of TH-metabolizing enzymes in …

Brown adipose tissue (BAT) of hypothyroid rats contains a low Km (type II) iodothyronine 5′-
deiodinase (I-5′ D) that has been characterized as being insensitive to inhibition by …

Brown adipose tissue (BAT) iodothyronine 5'-deiodinase (5'D) activities are very high during
fetal life but decrease 10-fold a few hours before birth. Accordingly, BAT 3, 5, 3' …