Congenital hyperinsulinism (CHI), characterized by profound hypoglycaemia related to
inappropriate insulin secretion, may be associated histologically with either diffuse insulin …

Insulin secretion from pancreatic β-cells is tightly regulated to maintain fasting blood glucose
level between 3.5–5.5 mmol/l. In hyperinsulinaemic hypoglycaemia (HH) insulin secretion …

Congenital hyperinsulinism (HI) is the most frequent cause of persistent hypoglycemia in
infants and children. Delays in diagnosis and initiation of appropriate treatment contribute to …

Familial hyperinsulinism (HI) is a disorder characterized by dysregulation of insulin secretion
and profound hypoglycemia. Mutations in both the Kir6. 2 and sulfonylurea receptor (SUR1) …

Hyperinsulinaemic hypoglycaemia (HH) is characterized by unregulated insulin secretion
from pancreatic β-cells. Untreated hypoglycaemia in infants can lead to seizures …

Congenital hyperinsulinism (CHI or HI) is a condition leading to recurrent hypoglycemia due
to an inappropriate insulin secretion by the pancreatic islet β cells. HI has two main …

Congenital hyperinsulinism is a cause of persistent hypoglycaemia in the neonatal period. It
is a heterogeneous disease with respect to clinical presentation, molecular biology, genetic …

Hyperinsulinism (HI) is the leading cause of persistent hypoglycemia in children, which if
unrecognized may lead to development delays and permanent neurologicdamage. Prompt …

Hyperinsulinemic hypoglycemia (HH) is a consequence of unregulated insulin secretion by
pancreatic β-cells and is a major cause of hypoglycemic brain injury and mental retardation …

Hyperinsulinaemic hypoglycaemia (HH) is due to the unregulated secretion of insulin from
pancreatic β-cells. A rapid diagnosis and appropriate management of these patients is …