Effects of n-3 polyunsaturated fatty acid supplementation in the prevention and treatment of depressive disorders—a systematic review and meta-analysis

M Wolters, A von der Haar, AK Baalmann, M Wellbrock… - Nutrients, 2021 - mdpi.com
N-3 polyunsaturated fatty acids (PUFAs) have been suggested to affect depressive
disorders. This review aims to determine the effect of n-3 PUFAs on depressive symptoms in …

[HTML][HTML] Updated systematic review and meta-analysis of the effects of n− 3 long-chain polyunsaturated fatty acids on depressed mood

KM Appleton, PJ Rogers, AR Ness - The American journal of clinical …, 2010 - Elsevier
Background: The debate over a role for n− 3 long-chain polyunsaturated fatty acids (n− 3
PUFAs) in depressed mood continues. Objective: The objective was to update a previous …

EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta …

JG Martins - Journal of the American College of Nutrition, 2009 - Taylor & Francis
Background: Epidemiologic and case-control data suggest that increased dietary intake of
omega-3 long-chain polyunsaturated fatty acids (ω3 LC-PUFAs) may be of benefit in …

High-dose omega-3 polyunsaturated fatty acid supplementation might be more superior than low-dose for major depressive disorder in early therapy period: a network …

X Luo, J Feng, Z Yang, Q Huang, J Lin, B Yang, K Su… - BMC psychiatry, 2020 - Springer
Background The application of n-3 Polyunsaturated Fatty Acids (n-3 PUFAs)
supplementation for major depressive disorder (MDD) has been widely discussed in recent …

Omega-3 polyunsaturated fatty acids supplementation alleviate anxiety rather than depressive symptoms among first-diagnosed, drug-naïve major depressive …

R Yang, L Wang, K Jin, S Cao, C Wu, J Guo… - Frontiers in …, 2022 - frontiersin.org
Background Omega-3 polyunsaturated fatty acids (n-3 PUFAs) augmentation of
antidepressants has shown great potential in the prevention and treatment of major …

Omega 3 polyunsaturated fatty acids and the treatment of depression

G Deacon, C Kettle, D Hayes, C Dennis… - Critical reviews in food …, 2017 - Taylor & Francis
Depression is a common, recurrent, and debilitating illness that has become more prevalent
over the past 100 years. This report reviews the etiology and pathophysiology of depression …

Omega-3 polyunsaturated fatty acids and reduction of depressive symptoms in older adults: a systematic review and meta-analysis

ZG Bai, A Bo, SJ Wu, QY Gai, I Chi - Journal of affective disorders, 2018 - Elsevier
Objective The aim of this study is to systematically review the efficacy of omega-3
polyunsaturated fatty acid (n-3 PUFA) supplements in reducing depressive symptoms …

Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder

RJT Mocking, I Harmsen, J Assies, MWJ Koeter… - Translational …, 2016 - nature.com
Omega-3 polyunsaturated fatty acid (PUFA) supplementation has been proposed as
(adjuvant) treatment for major depressive disorder (MDD). In the present meta-analysis, we …

Supplementation of n-3 polyunsaturated fatty acids for major depressive disorder: a randomized, double-blind, 12-week, placebo-controlled trial in Korea

Y Park, YS Park, SH Kim, DH Oh, YC Park - Annals of Nutrition and …, 2015 - karger.com
Background: Controversy over the efficacy of n-3 polyunsaturated fatty acids (PUFAs) in
depression continues to this day. The present study investigated the hypothesis that n-3 …

ω-3 Fatty acids for major depressive disorder in adults: an abridged Cochrane review

KM Appleton, HM Sallis, R Perry, AR Ness… - BMJ open, 2016 - bmjopen.bmj.com
Objective To assess the effects of n-3 polyunsaturated fatty acids (n-3PUFAs; also known as
ω-3 fatty acids) compared with comparator for major depressive disorder (MDD) in adults …