Current train of thought in appetite research is favouring an interest in non-homeostatic or
hedonic (reward) mechanisms in relation to overconsumption and energy balance. This …

Obesity, Type 2 diabetes and other metabolic disorders continue to pose serious challenges
to human health and well-being. An important source of these challenges is the …

The motivation to eat in humans is a complex process influenced by intrinsic mechanisms
relating to the hunger and satiety cascade, and extrinsic mechanisms based on the …

Contributing factors to obesity have been identified, yet prevention and treatment efforts
have had limited long-term success. It has recently been suggested that some individuals …

The traditional view of neural regulation of body energy homeostasis focuses on internal
feedback signals integrated in the hypothalamus and brainstem and in turn leading to …

With rising rates of obesity, research continues to explore the contributions of homeostatic
and hedonic mechanisms related to eating behaviour. In this Review, we synthesize the …

Caloric intake and energy balance are highly regulated to maintain metabolic homeostasis
and weight. However, hedonic-motivated food intake, in particular consumption of highly …

The brain responds to macronutrients via intricate mechanisms. We review how the brain's
neural systems implicated in homeostatic control of feeding and hedonic responses are …

Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …

Publisher Summary Food intake is essential to sustain life, and the sensory systems of taste
and smell are among the most fundamental building blocks of the brain's natural reward …