From Dante's Inferno (1), composed in the 14th century, to Roald Dahl's Charlie and the
Chocolate Factory (2), centuries of literature consistently portray obese characters as vile …

I review the main themes of my 50-year research career in ingestive behavior as a graduate
student at the University of Chicago and a professor at the City University of New York. A …

Human beings have reliable preferences for energy-rich foods; these preferences are
present at birth and possibly innate. Relatively recent changes in our day-to-day living …

Adaptive decision making to eat is crucial for survival, but in anorexia nervosa, the brain
persistently supports reduced food intake despite a growing need for energy. How the brain …

Among well-nourished populations, eating beyond homeostatic needs when presented with
caloric-dense palatable food evidences the assertion that an increasing proportion of …

Advances in neuroimaging techniques have provided insight into the role of the brain in the
regulation of food intake and weight. Growing evidence demonstrate that energy dense …

Rodent models of diet-induced obesity (DIO) mimic common human obesity more accurately
than obese single-gene mutation lines, such as the ob/ob mouse. Sprague-Dawley rats …

Ever since the pioneering discoveries in the mid nineteen hundreds, the hypothalamus was
recognized as a crucial component of the neural system controlling appetite and energy …

Energy homeostasis is regulated in coordinate fashion by the brain-gut axis, the homeostatic
energy balance circuitry in the hypothalamus and the hedonic energy balance circuitry …

The hedonic component of eating is an underexplored topic within neuroscience, which is
surprising given its importance for our survival and general well-being, as well as the …