Exposure to fine particulate air pollution causes vascular insulin resistance by inducing pulmonary oxidative stress

P Haberzettl, TE O'Toole, A Bhatnagar… - Environmental health …, 2016 - ehp.niehs.nih.gov
Background: Epidemiological evidence suggests that exposure to ambient air fine
particulate matter (PM2. 5) increases the risk of developing type 2 diabetes and …

Fine particulate matter (PM2.5) inhalation-induced alterations in the plasma lipidome as promoters of vascular inflammation and insulin resistance

BG Hill, B Rood, A Ribble… - American Journal of …, 2021 - journals.physiology.org
Fine particulate matter (PM2. 5) air pollution exposure increases the risk of developing
cardiovascular disease (CVD). Although the precise mechanisms by which air pollution …

Long-term exposure to ambient fine particulate pollution induces insulin resistance and mitochondrial alteration in adipose tissue

X Xu, C Liu, Z Xu, K Tzan, M Zhong… - Toxicological …, 2011 - academic.oup.com
We have previously shown that chronic exposure to ambient fine particulate matter (less
than 2.5 μm in aerodynamic diameter, PM2. 5) pollution in conjunction with high-fat diet …

Reduced metabolic insulin sensitivity following sub-acute exposures to low levels of ambient fine particulate matter air pollution

RD Brook, X Xu, RL Bard, JT Dvonch… - Science of the Total …, 2013 - Elsevier
Epidemiological studies suggest that fine particulate matter (PM2. 5) may increase the risk
for developing diabetes mellitus (DM). To evaluate possible mechanisms explaining these …

Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity

Q Sun, P Yue, JA Deiuliis, CN Lumeng, T Kampfrath… - Circulation, 2009 - Am Heart Assoc
Background—There is a strong link between urbanization and type 2 diabetes mellitus.
Although a multitude of mechanisms have been proposed, there are no studies evaluating …

[HTML][HTML] Inflammatory response to fine particulate air pollution exposure: neutrophil versus monocyte

X Xu, SY Jiang, TY Wang, Y Bai, M Zhong, A Wang… - PLoS …, 2013 - journals.plos.org
Objectives Studies have shown that chronic exposure to ambient fine particulate matter (less
than 2.5 µ m in aerodynamic diameter, PM2. 5) pollution induces insulin resistance through …

[HTML][HTML] Exaggerated effects of particulate matter air pollution in genetic type II diabetes mellitus

C Liu, Y Bai, X Xu, L Sun, A Wang, TY Wang… - Particle and fibre …, 2014 - Springer
Background Prior experimental and epidemiologic data support a link between exposure to
fine ambient particulate matter (< 2.5 μm in aerodynamic diameter, PM 2.5) and …

[HTML][HTML] Particulate matter air pollution: effects on the cardiovascular system

RB Hamanaka, GM Mutlu - Frontiers in endocrinology, 2018 - frontiersin.org
Air pollution is a complex mixture of gaseous and particulate components, each of which has
detrimental effects on human health. While the composition of air pollution varies greatly …

[HTML][HTML] Exposure to fine airborne particulate matter induces macrophage infiltration, unfolded protein response, and lipid deposition in white adipose tissue

R Mendez, Z Zheng, Z Fan, S Rajagopalan… - American journal of …, 2013 - ncbi.nlm.nih.gov
Recent epidemiological studies have suggested a link between exposure to ambient air-
pollution and susceptibility to metabolic disorders such as Type II diabetes mellitus …

Epidemiological and experimental links between air pollution and type 2 diabetes

C Liu, Z Ying, J Harkema, Q Sun… - Toxicologic …, 2013 - journals.sagepub.com
There is increasing evidence suggesting links between exposure to environmental toxins
and susceptibility to type 2 diabetes mellitus (DM). In this review, we summarize the …